NCT05954741 · RECRUITING
Multidimensional Rehabilitation Programs for Cognitive Impairment in Comorbid Outpatients: a Randomized Controlled Trial
This trial compares three rehab programs for people aged 65 to 80 with early cognitive decline linked to vascular problems or several causes. One group does physical rehab alone. Two groups add brain-training exercises, on paper or on a digital device. It measures thinking skills, mood, and daily life. It is not a drug trial, and no phase applies.
You may qualify if
- Age Between 65 and 80 years.
- Neurocognitive Disorder due to vascular disease with Clinical Dementia Rating Scale score between 0.5 and 1, symptoms onset \< 12 months.
- Neurocognitive Disorder due to multiple etiology with Clinical Dementia Rating Scale score between 0.5 and 1, symptoms onset \< 12 months.
You're excluded if
- Other known neurological conditions involving cognitive functioning (e.g. Parkinson's disease, Multiple Sclerosis, head trauma, alcohol abuse).
- Severe organic instability.
- Neoplasia in progress.
- Severe psychiatric condition.
- Illiteracy.
- Severe perception deficits.
- Severe motor disability.
- Specific intellectual deficit.
- Participation in other forms of training or neurostimulation in the previous 6 months.
- Pharmacological interventions of neurological pertinence in the month before the study.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2024-10-03