ISRCTN16524074 · RECRUITING
Randomised control trial of a digitally provided psychological intervention for people who have a gene for frontotemporal dementia or Alzheimer's disease in their family
This study tests whether an 8-week online support programme, IWARF, improves mental wellbeing in people who live at risk of inherited dementia. It uses short modules, videos, and three video check-ins, drawing on Acceptance and Commitment Therapy. Wellbeing is measured by questionnaires. The source gives no phase. This is a talking-and-skills programme, not a drug.
You may qualify if
- Aged 18+ years with a first-degree relative who is symptomatic and/or a known mutation carrier for an inheritable form of dementia (either familial Alzheimer’s disease [FAD] or familial Fronto-Temporal Dementia [fFTD])
- Capacity to consent to research
- Access to an internet-enabled device
You're excluded if
- Individual is below the age of 18 years
- Individual does not have a first-degree relative who is symptomatic and/or a known mutation carrier
- Individual reports to the trial team to be displaying symptoms of FAD/fFTD before enrollment
- Individual does not have capacity to consent to research
- Individual does not have access to an internet-enabled device
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2025-11-07
Source: ISRCTN registry, record ISRCTN16524074, retrieved 2026-10-27. Registry text licensed CC BY 4.0.