NCT07022431 · NOT YET RECRUITING
Effects of a Cognitive-Engaging Strength Training Program on Health, Physical Condition, and Quality of Life in People With Alzheimer's Disease
This trial tests whether a supervised strength training program that also challenges the brain can help people with Alzheimer's disease. Researchers will measure thinking, movement, physical fitness, and quality of life after 16 weeks of twice-weekly sessions, compared with a control group. It is not a drug trial, and no phase applies.
You may qualify if
- Meet the criteria for early AD dementia (GDS 4) (according to the DSM-IV-TR and NINCDS-ADRDA criteria)
- Have a score between 15 and 20 on the Mini-Mental State Examination scale (Trivedi, 2017), with criteria for moderate cognitive impairment.
- Maintain a stable pharmacological regimen for at least 30 days prior.
- Give consent to be evaluated using the cognitive screening tests described in this report.
- Be available to attend in person weekly at the headquarters where the training will take place in Seville capital.
You're excluded if
- Presence of heart disease or other diseases that lead to a contraindication in the practice of physical activity.
- Presence of psychiatric illnesses.
- Having some musculoskeletal pathology or alteration that does not allow the performance of the proposed exercises or proposed conditional evaluations.
- Having a resting heart rate less than 50 or greater than 100 beats per minute.
- Having a diagnosed intellectual disability.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2025-06-15