NCT07289061 · RECRUITING

Positive Psychology for Early Cognitive Decline: Effects on Cognitive and Brain Function

This study tests whether a 24-week Positive Psychology program, done in small online groups with short home practices, improves thinking and brain function in older adults with subjective cognitive decline or mild cognitive impairment. About 128 people are split between the program and usual care. It is a behavioral study with no drug and no phase.

Eligibility criteria

Inclusion Criteria
-Documented diagnosis of Subjective Cognitive Decline (SCD) or Mild Cognitive Impairment (MCI) according to clinical evaluation and site standard criteria.
Exclusion Criteria
* Diagnosis of dementia (major neurocognitive disorder) or other major neurocognitive disorder that is moderate or severe.
* Major psychiatric disorder currently unstable or untreated (e.g., major depression with psychotic features, bipolar disorder, schizophrenia).
* Neurological conditions that affect cognition.
* Uncorrected hearing or vision problems that prevent participation in assessments or online sessions.
* Concurrent participation in another interventional study targeting cognition or wellbeing during the study period.

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2026-01-07

View full record on ClinicalTrials.gov

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