NCT07469618 · NOT YET RECRUITING
Efficacy of Cognitive Stimulation Therapy Integrated With Stress Reduction Intervention for Adults With Mild Cognitive Impairment
This trial compares two talk-and-activity programs for adults with mild cognitive impairment in Pakistan. One is standard Cognitive Stimulation Therapy, a group program of mental activities. The other adds a culturally rooted stress reduction practice. Researchers will measure whether thinking skills improve more with the added stress piece. Phase is not applicable, since this is a behavioral study, not a drug.
You may qualify if
- Adults aged 45 years and above
- Individuals with education up to Matric
- Individuals who obtain a score lower than 23 on Montreal Cognitive Assessment (MoCA) suggesting the presence of cognitive decline.
- Individuals who obtain a score of 14 or more on the Perceived Stress Scale suggesting increased levels of perceived stress (moderate and high)
- Individuals who obtain score ranged from 13 to 25 (Poor to Adequate) on Quality of Life in Alzheimer's Disease (Qol-AD)
You're excluded if
- Diagnosis of dementia or major neurocognitive disorder
- Presence of severe psychiatric illness (e.g., psychosis, major depressive episode)
- Significant hearing or visual impairments that interfere with participation
- Currently undergoing psychological or cognitive therapy
- Any neurological condition that may interfere with cognitive assessment (e.g., stroke, Parkinson's disease)
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-03-13