NCT07449117 · RECRUITING
Effect of Striatal Temporal Interference Stimulation on Language Processing in Neurodegenerative Diseases
This study tests whether a non-invasive brain stimulation device, called temporal interference stimulation, can change how people with mild cognitive impairment process sentences. It targets a deep brain area called the striatum. Researchers compare real stimulation with a sham version and look at immediate effects. The phase is not applicable because it is a device study, not a drug trial.
You may qualify if
- Possible or probable Mild Cognitive Impairment with Lewy Bodies (MCI-LB), in Parkinson's Disease (MCI-PD) or Amnestic Mild Cognitive Impairment (aMCI).
You're excluded if
- Any severe psychiatric disorder.
- History of other neurological diseases affecting the central nervous system.
- Severe head trauma.
- Uncompensated internal or oncological disease.
- Presence of MRI-incompatible metal in the body (e.g., pacemaker).
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-03-04