NCT06304129 · UNKNOWN
Diagnostic Performance of Plasma Biomarkers of Alzheimer's Disease Compared With CSF Markers
Sponsor: Central Hospital, Nancy, France
This study tests whether blood draws can match the accuracy of spinal fluid tests for detecting Alzheimer's-related changes in the brain. Researchers will compare blood levels of proteins like amyloid and tau against the standard lumbar puncture results in patients already being evaluated for Alzheimer's at a French hospital. This is a diagnostic accuracy study, not a drug trial — it is trying to validate a less invasive test, not treat anything.
You may qualify if
- Man or woman aged 18 or over
- Person affiliated to a social security scheme or beneficiary of such a scheme
- Person who has received full information on the organization of the research and has signed an informed consent form
- Person whose care requires a lumbar puncture to measure markers of Alzheimer's disease
You're excluded if
- Adult subject to a legal protection measure (guardianship, curatorship, safeguard of justice)
- An adult unable to give consent
- Persons deprived of their liberty by judicial or administrative decision
- Persons under psychiatric care under articles L. 3212-1 and L. 3213-1.
- Pregnant, parturient or breast-feeding women
- Persons staying in a health or social establishment for purposes other than research.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2024-03-12