NCT04309461 · ACTIVE NOT RECRUITING
Make Better Choices 2 for Rural Appalachians
This trial tests an adapted version of a program called Make Better Choices 2 for adults in Appalachian Kentucky. It uses an app, an activity tracker, health coaching, and small incentives. It measures whether people eat more fruits and vegetables, eat less saturated fat, move more, and sit less. Phase does not apply, since this is a behavior study, not a drug trial.
You may qualify if
- adults residing in Appalachian Kentucky
- willingness to use smart phone to record and modify diet and activity
- willingness to wear an accelerometer
- consume \<4.5 cups fruit/vegetables daily
- consume >8% daily calories from fat
- engage in \<150 minutes of moderate-intensity physical activity weekly
- spend >90 minutes daily on non-work, non-education-related sedentary recreational use of screen time.
You're excluded if
- unstable medical conditions
- cognitive impairment
- hospitalization for psychiatric disorder within the last 5 years
- active suicidal ideation
- substance use disorder other than nicotine dependence
- at risk for adverse cardiovascular events with moderate-intensity activity
- taking weight loss medication
- trying to get pregnant, pregnant or lactating
- active eating disorders
- using mobility assistive devices
- inability to read study materials
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-01-20