NCT07723950 · NOT YET RECRUITING
A Retrospective Database Study for the Development and Validation of Algorithms for Intracerebral Hemorrhage and Seizures in Alzheimer's Disease
This is not a clinical treatment trial. Researchers are mining existing insurance claims and electronic health records from Alzheimer's patients to build better detection tools for two serious complications: large brain bleeds (intracerebral hemorrhage) and new-onset seizures. No one receives any intervention. The goal is to improve how accurately these events can be identified in administrative data — a behind-the-scenes research effort with no phase designation.
You may qualify if
- Before or on the outcome event date, have at least 1 ICD-10-CM diagnosis code for AD in medical claims in an inpatient setting; or have at least 2 ICD-10-CM diagnosis codes in medical claims in an outpatient setting, at least 7 days and less than 365 days apart
- Have at least 365 days of continuous coverage with medical and pharmacy benefits before the outcome event date
- Have EHR data available for (1) the outcome event date or (2) during the period of up to 30 days before and up to 90 days after the outcome event date
- Have unstructured EHR information (ie, clinical notes) available for any encounter (1) on the outcome event date or (2) during the period of 30 days before to up to 45 days after the outcome event date
You're excluded if
- New-onset seizure outcome only: Have any ICD-10-CM diagnosis code for seizure or epilepsy before the outcome event date
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-07-23