NCT01888029 · WITHDRAWN
Influence of tDCS on Cortical Plasticity in Patients With Mild Cognitive Impairment (MCI)
This study tests whether a gentle electrical current applied to the scalp, called tDCS, changes how adaptable the brain's movement area is in people with mild cognitive impairment. Researchers compare real stimulation with a fake version. They measure muscle responses to magnetic pulses. Phase is not applicable, since this is a device study, not a drug trial.
You may qualify if
- Right-handed according to the Oldfield Händigkeits inventory (lateralization index> 70) (1971)
- Cognitive impairment according to the diagnostic criteria of a MCI (amnesic or even multiple domains)
- No therapeutic treatment with AChE inhibitors
- No motor impairments relevant to everyday life
- Age 50 to 80 years
You're excluded if
- Severe neurological / psychiatric or pre-existing internist conditions because additional cognitive deficits are expected
- Epilepsy, epileptic seizure in medical history
- Cognitive deficit (MMSE \<20)
- Depressive episode (Beck Depression Inventory (BDI)> 12)
- Newly taking (\<3 months) centrally active drugs, particularly acetylcholinesterase inhibitors
- Pregnancy
- Pacemaker (contraindication for MRI)
- Other metal parts in the body (contraindication for MRI)
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2021-05-14