Find clinical trials relevant to you.
Browse APOE4-relevant studies by location and recruitment status. Open a study for eligibility and contact details.
Every protocol translated from trial-speak into sentences a human reads once.
See how a study's published criteria address APOE4. Does our genotype get us in, keep us out, or change the risk.
Synced from ClinicalTrials.gov every day, so a closed trial never wastes your time.
On the horizon: announced, not yet enrolling
PROTECT-Cog
Alzheimer's Association
A U.S. POINTER-style lifestyle programme combined with a GLP-1 medicine, testing whether together they lower the risk of cognitive decline. Three years, check-ins every six months.
Announced at AAIC on 13 July 2026. Not yet registered or enrolling.
AAIC announcement
Browse every APOE4 trial (2,216)
Explore the trials.
Browse APOE4-relevant Alzheimer’s trials by state or recruiting status, or start with our plain-English guide to joining one.
By state
- California225
- Florida187
- Texas175
- New York171
- Massachusetts152
- Pennsylvania120
- North Carolina114
- Illinois110
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Frequently asked questions
- Yes. Browsing, searching, and filtering every APOE4-relevant trial is completely free, with no signup required. You only need an email if you want alerts for new trials or a personalized match.
- Every trial is pulled directly from ClinicalTrials.gov, the NIH/NLM public registry, and re-synced daily. The trial count and "last updated" timestamp on this page reflect that daily refresh, not a stale snapshot.
- After you answer four optional questions (age, sex, APOE4 status, and cognitive status), Phoenix checks each trial's eligibility criteria against your answers and shows a green "Matches your profile" badge with the reasons, or a "Doesn't match, see why" note you can expand. This is a starting-point screen, not a full eligibility determination, the study team always confirms.
- Click the interest button on any trial card. Our research team handles the introduction to the study site directly, so the sponsor sees a ready-to-recruit APOE4 carrier instead of a cold application through the study's own intake form.
- No, the engine is open to everyone. Phoenix Core members additionally get first-line access to early-access programs we run directly with partners, on top of the public trials everyone can see here.
- Yes. Turn on trial alerts with your email and your saved filters, and we'll notify you when a new APOE4-relevant trial opens that fits your search, rather than you having to keep checking back.
Free to browse, without signing up. The study team confirms eligibility and enrollment.
Keep up with trials relevant to you.
Core includes personalized clinical-trial alerts in the app, so you do not have to start a new search each time.