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Phoenix APOE4 Research · Reviewed by Kevin Tran, APOE4/4 carrier and founder · Data through 2026-08-23 · How to read this research
How to read this
Observational research: real APOE4 carriers tracked over time, each compared with their own earlier self. Members chose their interventions, with no randomisation or placebo group. Everything else they changed is shown beside each result.
Read the full methods and limitsFor APOE4 carriers, Phoenix has published positive evidence for Plain omega-3 and Vitamin D3 against Vitamin D level. Member #9FAAE3's Vitamin D level moved from 28.2 to 43.7 ng/mL in 259 days. Three members raised their vitamin D level on a Vitamin D3-led combination: 28 to 102 ng/mL in 126 days, 32.1 to 65.8 ng/mL in 69 days, and 33 to 54 ng/mL in 120 days.
Phoenix has measured 2 interventions against Vitamin D level: 2 positive. See the table below.
| Intervention | What we observed | Evidence status |
|---|---|---|
| Plain omega-3 | Member #9FAAE3's Vitamin D level moved from 28.2 to 43.7 ng/mL in 259 days. | Repeated positive |
| Vitamin D3 | Three members raised their vitamin D level on a Vitamin D3-led combination: 28 to 102 ng/mL in 126 days, 32.1 to 65.8 ng/mL in 69 days, and 33 to 54 ng/mL in 120 days. | Repeated positive |
Search by health goal or intervention to see what changed for real members, including results that moved the wrong way.
Nutrient status · Improve vitamin D status · 2 interventions shown.
Vitamin D level: Increase 4–15.5 ng/mL
Cases: 2Case range
Member #9FAAE3's Vitamin D level moved from 28.2 to 43.7 ng/mL in 259 days.
Plain omega-3
✓Repeated positiveMember #9FAAE3's Vitamin D level moved from 28.2 to 43.7 ng/mL in 259 days.
Vitamin D level
Before28.2After43.7ng/mL+55%
259 days between measurements
Promising early signal
What else changed: no nearby starts were recorded.
Next study: repeat Vitamin D level after a dated Plain omega-3 window.
Vitamin D level
Before60After64ng/mL+6.7%
363 days between measurements
Full stack credited: Omega-3 (lead), Statin (undated).
What else changed: no nearby starts were recorded.
Next study: repeat Vitamin D level after a dated Plain omega-3 window.
Vitamin D level: Increase 14.6–74 ng/mL
Cases: 5Case range
Three members raised their vitamin D level on a Vitamin D3-led combination: 28 to 102 ng/mL in 126 days, 32.1 to 65.8 ng/mL in 69 days, and 33 to 54 ng/mL in 120 days.
Vitamin D3
✓Repeated positiveThree members raised their vitamin D level on a Vitamin D3-led combination: 28 to 102 ng/mL in 126 days, 32.1 to 65.8 ng/mL in 69 days, and 33 to 54 ng/mL in 120 days.
Vitamin D level
Before28After102ng/mL+264.3%
126 days between measurements
Full stack credited: Vitamin D3 (lead), Lysoveta (DHA-LPC) (co).
What else changed: no nearby starts were recorded.
Next study: repeat Vitamin D level after a dated Vitamin D3 window.
Vitamin D level
Before49After69ng/mL+40.8%
207 days between measurements
Full stack credited: Vitamin D3 (lead), Lysoveta (DHA-LPC) (co), Omega-3 (co).
What else changed: no nearby starts were recorded.
Next study: repeat Vitamin D level after a dated Vitamin D3 window.
Vitamin D level
Before33After54ng/mL+63.6%
120 days between measurements
Full stack credited: Vitamin D3 (lead), Omega-3 (co).
What else changed: no nearby starts were recorded.
Next study: repeat Vitamin D level after a dated Vitamin D3 window.
Vitamin D level
Before62.1After76.7ng/mL+23.5%
147 days between measurements
Full stack credited: Vitamin D3 (lead), Lysoveta (DHA-LPC) (co), Omega-3 (co).
What else changed: no nearby starts were recorded.
Next study: repeat Vitamin D level after a dated Vitamin D3 window.
Vitamin D level
Before32After66ng/mL+106.3%
69 days between measurements
Full stack credited: Vitamin D3 (lead), Omega-3 (co).
What else changed: no nearby starts were recorded.
Next study: repeat Vitamin D level after a dated Vitamin D3 window.
The 43-page study: what members tried, how their bloodwork and wearable results changed, and what else changed alongside them.
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