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Folate: what it changed, and what it did not

One intervention, every measured benefit and result that did not improve. See who it moved for, where it stayed neutral or went the other way, and the next hypothesis Phoenix can validate.

Phoenix APOE4 Research · Reviewed by Kevin Tran, APOE4/4 carrier and founder · Data through 2026-08-23 · How to read this research

How to read this

Observational research: real APOE4 carriers tracked over time, each compared with their own earlier self. Members chose their interventions, with no randomisation or placebo group. Everything else they changed is shown beside each result.

Read the full methods and limits

Key findings

Phoenix has measured Folate against 1 exact outcome for APOE4 carriers. Member #8E1FD7's Homocysteine moved from 8.3 to 7 µmol/L in 175 days.

Folate evidence by outcome
OutcomeDirectionWhat we observed
HomocysteinePositive individual resultMember #8E1FD7's Homocysteine moved from 8.3 to 7 µmol/L in 175 days.

Questions about Folate

What is the effect of Folate for APOE4 carriers?

Phoenix has measured Folate against 1 exact outcome for APOE4 carriers. Member #8E1FD7's Homocysteine moved from 8.3 to 7 µmol/L in 175 days.

Does Folate change Homocysteine for APOE4 carriers?

Member #8E1FD7's Homocysteine moved from 8.3 to 7 µmol/L in 175 days. Support: 1 logged members, 1 members with repeats, 1 observations, 2 measurements.

What changed for real APOE4 carriers?

Search by health goal or intervention to see what changed for real members, including results that moved the wrong way.

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Folate · 1 outcome shown.

Intervention categorySupplements
InterventionFolate

Folate

SupplementsOutcomes: 1

Homocysteine: Decrease 1.3 µmol/L

Cases: 1

Details

Member #8E1FD7's Homocysteine moved from 8.3 to 7 µmol/L in 175 days.

Folate

✓Positive individual result

Member #8E1FD7's Homocysteine moved from 8.3 to 7 µmol/L in 175 days.

Selected member cases

  1. Phoenix memberAPOE4/454female

    Homocysteine

    Before8.3After7.0µmol/L-15.7%

    175 days between measurements

    Full stack credited: Folate (lead), Vitamin B12 (undated), Magnesium Glycinate (undated), N-acetylcysteine (undated).

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Homocysteine after a dated Folate window.

logged members
1
members with repeats
1
observations
1
measurements
2

Full record

The Beat the Odds Study

The 43-page study: what members tried, how their bloodwork and wearable results changed, and what else changed alongside them.

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