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Phoenix APOE4 Research · Reviewed by Kevin Tran, APOE4/4 carrier and founder · Data through 2026-08-23 · How to read this research
How to read this
Observational research: real APOE4 carriers tracked over time, each compared with their own earlier self. Members chose their interventions, with no randomisation or placebo group. Everything else they changed is shown beside each result.
Read the full methods and limitsPhoenix has measured B-complex against 2 exact outcomes for APOE4 carriers. Member #4A4C53's Homocysteine moved from 7.5 to 6.5 µmol/L in 320 days. Member #6FAEFA's Vitamin B12 level moved from 680 to 1539 pg/mL in 70 days.
| Outcome | Direction | What we observed |
|---|---|---|
| Homocysteine | Repeated positive | Member #4A4C53's Homocysteine moved from 7.5 to 6.5 µmol/L in 320 days. |
| Vitamin B12 level | Positive individual result | Member #6FAEFA's Vitamin B12 level moved from 680 to 1539 pg/mL in 70 days. |
Phoenix has measured B-complex against 2 exact outcomes for APOE4 carriers. Member #4A4C53's Homocysteine moved from 7.5 to 6.5 µmol/L in 320 days. Member #6FAEFA's Vitamin B12 level moved from 680 to 1539 pg/mL in 70 days.
Member #4A4C53's Homocysteine moved from 7.5 to 6.5 µmol/L in 320 days. Support: 3 logged members, 3 members with repeats, 3 observations, 6 measurements.
Member #6FAEFA's Vitamin B12 level moved from 680 to 1539 pg/mL in 70 days. Support: 1 logged members, 1 members with repeats, 1 observations, 2 measurements.
Search by health goal or intervention to see what changed for real members, including results that moved the wrong way.
B-complex · 2 outcomes shown.
Homocysteine: Decrease 1.0–4.0 µmol/L
Cases: 3Case range
Member #4A4C53's Homocysteine moved from 7.5 to 6.5 µmol/L in 320 days.
B-complex
✓Repeated positiveMember #4A4C53's Homocysteine moved from 7.5 to 6.5 µmol/L in 320 days.
Homocysteine
Before7.5After6.5µmol/L-13.3%
320 days between measurements
Full stack credited: B Complex (lead), Magnesium Glycinate (co).
What else changed: no nearby starts were recorded.
Next study: repeat Homocysteine after a dated B-complex window.
Homocysteine
Before7.0After5.1µmol/L-27.1%
68 days between measurements
Consistent with established evidence
Full stack credited: B Complex (lead), Vitamin B12 (undated), Folate (undated), Magnesium Glycinate (undated).
This member logs 63 recorded interventions in total, one of Phoenix's largest stacks, not a clean two-item comparison. B Complex is the only item with a formal homocysteine mechanism active the full window.
What else changed: no nearby starts were recorded.
Next study: repeat Homocysteine after a dated B-complex window.
Homocysteine
Before16.0After12.0µmol/L-25%
60 days between measurements
Consistent with established evidence
This member's entire recorded history is four items, the thinnest of the ten, and the comparison stays clean: one credited item, one not, no ambiguity.
What else changed: no nearby starts were recorded.
Next study: repeat Homocysteine after a dated B-complex window.
Vitamin B12 level: Increase 859 pg/mL
Cases: 1
Member #6FAEFA's Vitamin B12 level moved from 680 to 1539 pg/mL in 70 days.
B-complex
✓Positive individual resultMember #6FAEFA's Vitamin B12 level moved from 680 to 1539 pg/mL in 70 days.
Vitamin B12 level
Before680After1539pg/mL+126.3%
70 days between measurements
Full stack credited: B Complex (lead), Vitamin B12 (co).
What else changed: no nearby starts were recorded.
Next study: repeat Vitamin B12 level after a dated B-complex window.
The 43-page study: what members tried, how their bloodwork and wearable results changed, and what else changed alongside them.
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