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B-complex: what it changed, and what it did not

One intervention, every measured benefit and result that did not improve. See who it moved for, where it stayed neutral or went the other way, and the next hypothesis Phoenix can validate.

Phoenix APOE4 Research · Reviewed by Kevin Tran, APOE4/4 carrier and founder · Data through 2026-08-23 · How to read this research

How to read this

Observational research: real APOE4 carriers tracked over time, each compared with their own earlier self. Members chose their interventions, with no randomisation or placebo group. Everything else they changed is shown beside each result.

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The Phoenix Beat the Odds Study

The study behind the Navigator.

Read the 43-page study: what members tried, how their results changed, and what else they changed at the same time.

476
Phoenix members
30,737
Biomarker readings
139
Members with 2+ blood draws
176
Intervention signals

Data through 2026-08-23

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Key findings

Phoenix has measured B-complex against 2 exact outcomes for APOE4 carriers. Member #4A4C53's Homocysteine moved from 7.5 to 6.5 µmol/L in 320 days. Member #6FAEFA's Vitamin B12 level moved from 680 to 1539 pg/mL in 70 days.

B-complex evidence by outcome
OutcomeDirectionWhat we observed
HomocysteineRepeated positiveMember #4A4C53's Homocysteine moved from 7.5 to 6.5 µmol/L in 320 days.
Vitamin B12 levelPositive individual resultMember #6FAEFA's Vitamin B12 level moved from 680 to 1539 pg/mL in 70 days.

Questions about B-complex

What is the effect of B-complex for APOE4 carriers?

Phoenix has measured B-complex against 2 exact outcomes for APOE4 carriers. Member #4A4C53's Homocysteine moved from 7.5 to 6.5 µmol/L in 320 days. Member #6FAEFA's Vitamin B12 level moved from 680 to 1539 pg/mL in 70 days.

Does B-complex change Homocysteine for APOE4 carriers?

Member #4A4C53's Homocysteine moved from 7.5 to 6.5 µmol/L in 320 days. Support: 3 logged members, 3 members with repeats, 3 observations, 6 measurements.

Does B-complex change Vitamin B12 level for APOE4 carriers?

Member #6FAEFA's Vitamin B12 level moved from 680 to 1539 pg/mL in 70 days. Support: 1 logged members, 1 members with repeats, 1 observations, 2 measurements.

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