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Homocysteine: what moved for Phoenix members

Track the laboratory homocysteine outcome without blending it into other markers. Compare the interventions attached to each exact measurement before choosing what to test in yourself.

Research issue
Issue 01
Data through
2026-08-09
Evidence map version
v1.1.0
Explore the evidence Get the Evidence Map

How to read this

Phoenix research is longitudinal and observational: we follow real APOE4 carriers over time and compare each member with their own earlier self, with no placebo group, no randomisation, and members choosing their own interventions.

That means these are strong signals pointing at what to test next, not proof of cause. Most nutrition, supplement and lifestyle research you read online has exactly the same design. The difference is that we say so, and we show you the confounders.

Read the full methods and limits

What the Phoenix community is measuring

Browse exact outcomes and interventions. Each result keeps its source, measurement rule and audit record beside the claim.

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Homocysteine

Track the laboratory homocysteine outcome without blending it into other markers.

Most promising

Homocysteine

Laboratory homocysteine result · Aim: lower

Magnesium threonate

✓Repeated positive

Two clean curated cases lowered homocysteine by 28.8% and 31.9%; these are two cases, not a response rate.

Selected member cases

  1. Magnesium Match · APOE4/4 · female · age 50-59

    Homocysteine fell from 9.40 to 6.40 µmol/L, down 31.9% across a 26-month clean window.

    What else changed: no nearby starts were recorded.

    Next study: No human magnesium-threonate homocysteine study was found; B-vitamin exposure is the main alternative to separate.

  2. Magnesium Mover · APOE4/4 · male · age 50-59

    10.53 → 7.5 µmol/L · -28.8% · 64 days

    What else changed: nearby starts included B-vitamin intake not captured.

    Next study: No human magnesium-threonate homocysteine study was found; B-vitamin exposure is the main alternative to separate.

2 selected member cases · not a response rate

Logged members
142
Members with repeats
33
Observations
2
Measurements
4
Sources and context

Broad magnesium-family users with a repeat homocysteine result are support context, not clean threonate responders.

  • report-lines-248-343, reviewed by independent verifier
  • report-lines-129-156, reviewed by independent verifier

2 selected cases shown with this evidence.

Not yet measured

No human magnesium-threonate homocysteine study was found; B-vitamin exposure is the main alternative to separate.

How to test it

Baseline
Record a homocysteine result before the dated start.
Duration
84 days
Adherence
Track magnesium and B-vitamin use throughout the window.
Retest
Repeat homocysteine after the planned window.
Falsifier
Homocysteine does not fall in clean magnesium-threonate windows once B-vitamin exposure is dated and separated.
Eligible-member target
40 members

Probiotics

✓Positive individual result

One curated Lactobacillus reuteri case lowered homocysteine 9.9%; the paired values were not published.

Selected member cases

  1. Probiotic Repeat · genotype not disclosed · female · age 60-69

    Homocysteine fell 9.9%; the public report does not print the paired values.

    What else changed: no nearby starts were recorded.

    Next study: repeat Homocysteine after a dated Probiotics window.

1 selected member case · not a response rate

Observations
1
Measurements
2
Sources and context

Members with a logged probiotic and repeat homocysteine result; the visible case is curated.

  • report-lines-248-343, reviewed by independent verifier

1 selected case shown with this evidence.

What may work against

Homocysteine

Laboratory homocysteine result · Aim: lower

Lysoveta DHA-LPC

↘Opposite direction

The Omega Lifter's homocysteine moved opposite the goal from 5.9 to 9.4 µmol/L, while remaining described as normal.

Selected member cases

  1. Omega Lifter · APOE4/4 · male · age 40-49

    Homocysteine rose from 5.9 to 9.4 µmol/L; elapsed days were not printed.

    What else changed: no nearby starts were recorded.

    Next study: repeat Homocysteine after a dated Lysoveta DHA-LPC window.

1 selected member case · not a response rate

Logged members
1
Members with repeats
1
Observations
1
Measurements
2
Sources and context

Members with a logged Lysoveta start and repeat homocysteine result; the visible case is curated.

  • report-lines-248-343, reviewed by independent verifier

1 selected case shown with this evidence.

Still unanswered

Homocysteine

Laboratory homocysteine result · Aim: lower

Vitamin B12

?Collecting evidence

The support cohort has 76 B12-family users and 19 with a repeat homocysteine result; clean eligibility is not published.

0 selected member cases · not a response rate

Logged members
76
Members with repeats
19
Measurements
38
Sources and context

Members matched to the B12 family support question with a repeat homocysteine result.

  • report-lines-129-156, reviewed by independent verifier

Collecting evidence

No answer yet on Homocysteine

Vitamin B12 is being tracked against Homocysteine, but Phoenix has not yet published a ranked result for this exact question.

Every carrier who logs a dated start and a repeat test moves this page closer to an answer, including you.

Topic-specific updates about Vitamin B12 · No spam
Keep the map

Take every result into your next experiment.

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Turn evidence into your next test

Magnesium and homocysteine is 7 members from an answer.

Forty carriers with a dated start and a repeat blood test close it. Creatine, vitamin D3 and B12 sit further back. Your next blood test is somebody else's answer, and theirs is yours.

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