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Homocysteine: what moved for Phoenix members

Track the laboratory homocysteine outcome without blending it into other markers. Compare the interventions attached to each exact measurement before choosing what to test in yourself.

How to read this

Observational research: real APOE4 carriers tracked over time, each compared with their own earlier self. Members chose their interventions, with no randomisation or placebo group. Everything else they changed is shown beside each result.

Read the full methods and limits

What changed for real APOE4 carriers?

Search by health goal or intervention to see what changed for real members, including results that moved the wrong way.

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Homocysteine · Lower homocysteine · 6 interventions shown.

Health goalHomocysteine
SubgoalLower homocysteine

Lower homocysteine

Interventions tested: 6

B-complex

SupplementsOutcomes: 1

Homocysteine: Decrease 1.0–4.0 µmol/L

Cases: 3Case range

Details

Member #4A4C53's Homocysteine moved from 7.5 to 6.5 µmol/L in 320 days.

B-complex

✓Repeated positive

Member #4A4C53's Homocysteine moved from 7.5 to 6.5 µmol/L in 320 days.

Selected member cases

  1. Phoenix memberAPOE4/455female

    Homocysteine

    Before7.5After6.5µmol/L-13.3%

    320 days between measurements

    Full stack credited: B Complex (lead), Magnesium Glycinate (co).

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Homocysteine after a dated B-complex window.

  2. Phoenix memberAPOE4/454female

    Homocysteine

    Before7.0After5.1µmol/L-27.1%

    68 days between measurements

    Consistent with established evidence

    Full stack credited: B Complex (lead), Vitamin B12 (undated), Folate (undated), Magnesium Glycinate (undated).

    This member logs 63 recorded interventions in total, one of Phoenix's largest stacks, not a clean two-item comparison. B Complex is the only item with a formal homocysteine mechanism active the full window.

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Homocysteine after a dated B-complex window.

  3. Phoenix member54male

    Homocysteine

    Before16.0After12.0µmol/L-25%

    60 days between measurements

    Consistent with established evidence

    This member's entire recorded history is four items, the thinnest of the ten, and the comparison stays clean: one credited item, one not, no ambiguity.

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Homocysteine after a dated B-complex window.

logged members
3
members with repeats
3
observations
3
measurements
6

Full record

Folate

SupplementsOutcomes: 1

Homocysteine: Decrease 1.3 µmol/L

Cases: 1

Details

Member #8E1FD7's Homocysteine moved from 8.3 to 7 µmol/L in 175 days.

Folate

✓Positive individual result

Member #8E1FD7's Homocysteine moved from 8.3 to 7 µmol/L in 175 days.

Selected member cases

  1. Phoenix memberAPOE4/454female

    Homocysteine

    Before8.3After7.0µmol/L-15.7%

    175 days between measurements

    Full stack credited: Folate (lead), Vitamin B12 (undated), Magnesium Glycinate (undated), N-acetylcysteine (undated).

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Homocysteine after a dated Folate window.

logged members
1
members with repeats
1
observations
1
measurements
2

Full record

Magnesium glycinate

SupplementsOutcomes: 1

Homocysteine: Decrease 1.0–2.0 µmol/L

Cases: 2Case range

Details

Member #EFF528's Homocysteine moved from 7 to 6 µmol/L in 207 days.

Magnesium glycinate

✓Repeated positive

Member #EFF528's Homocysteine moved from 7 to 6 µmol/L in 207 days.

Selected member cases

  1. Phoenix memberAPOE4/450female

    Homocysteine

    Before7.3After5.3µmol/L-27.4%

    196 days between measurements

    Full stack credited: Magnesium Glycinate (lead), Vitamin B12 (undated).

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Homocysteine after a dated Magnesium glycinate window.

  2. Phoenix memberAPOE3/451female

    Homocysteine

    Before7.0After6.0µmol/L-14.3%

    207 days between measurements

    Full stack credited: Magnesium Glycinate (lead), B Complex (co).

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Homocysteine after a dated Magnesium glycinate window.

logged members
2
members with repeats
2
observations
2
measurements
4

Full record

Magnesium threonate

SupplementsOutcomes: 1

Homocysteine: Decrease 3.0 µmol/L

Cases: 1

Details

Two clean curated cases lowered homocysteine by 28.8% and 31.9%; these are two cases, not a response rate.

Magnesium threonate

✓Positive individual result

Two clean curated cases lowered homocysteine by 28.8% and 31.9%; these are two cases, not a response rate.

Little published human data on this link yet.

Selected member cases

  1. Phoenix memberAPOE4/453male

    Homocysteine

    Before10.5After7.5µmol/L-28.8%

    139 days between measurements

    Full stack credited: Vitamin B12 (lead), Magnesium threonate (co), Folate (undated), B Complex (undated).

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: No human magnesium-threonate homocysteine study was found; B-vitamin exposure is the main alternative to separate.

logged members
142
members with repeats
33
observations
2
measurements
4
Not yet measured: how to test it

No human magnesium-threonate homocysteine study was found; B-vitamin exposure is the main alternative to separate.

How to test it

Baseline
Record a homocysteine result before the dated start.
Duration
84 days
Adherence
Track magnesium and B-vitamin use throughout the window.
Retest
Repeat homocysteine after the planned window.
Falsifier
Homocysteine does not fall in clean magnesium-threonate windows once B-vitamin exposure is dated and separated.
Eligible-member target
40 members

This result is under review: Not published as a finding under the minimum-exposure rule: magnesium threonate has only 6 days of confirmed exposure before the after-draw in a 791-day window, and the other plausible co-drivers are undated and untagged. The other member in this pair keeps this result.

Full record

Probiotics

SupplementsOutcomes: 1

Homocysteine: Decrease 9.9 %

Cases: 1

Details

One curated Lactobacillus reuteri case lowered homocysteine 9.9%; the paired values were not published.

Probiotics

✓Positive individual result

One curated Lactobacillus reuteri case lowered homocysteine 9.9%; the paired values were not published.

Little published human data on this link yet.

Selected member cases

  1. Phoenix member69female

    Homocysteine fell 9.9%; the public report does not print the paired values.

    Full stack credited: Folate (undated), Vitamin B12 (lead), B Complex (undated), Magnesium Glycinate (undated).

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Homocysteine after a dated Probiotics window.

observations
1
measurements
2

Full record

Vitamin B12

SupplementsOutcomes: 1

Homocysteine: Status Not enough data

Details

The support cohort has 76 B12-family users and 19 with a repeat homocysteine result; clean eligibility is not published.

Vitamin B12

✓Repeated positive

The support cohort has 76 B12-family users and 19 with a repeat homocysteine result; clean eligibility is not published.

Selected member cases

  1. Phoenix memberAPOE4/455male

    Homocysteine

    Before12.0After11.1µmol/L-7.5%

    89 days between measurements

    Full stack credited: Vitamin B12 (lead), Magnesium threonate (co), Folate (undated), TMG (undated).

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Homocysteine after a dated Vitamin B12 window.

  2. Phoenix memberAPOE4/466female

    Homocysteine

    Before14.6After11.7µmol/L-19.9%

    44 days between measurements

    Full stack credited: Vitamin B12 (lead), Magnesium Glycinate (co).

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Homocysteine after a dated Vitamin B12 window.

logged members
78
members with repeats
21
observations
2
measurements
42

Full record

The Beat the Odds Study

The 43-page study: what members tried, how their bloodwork and wearable results changed, and what else changed alongside them.

Download the Beat the Odds Study

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