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NMN: what it changed, and what it did not

One intervention, every measured benefit and result that did not improve in Issue 01. See who it moved for, where it stayed neutral or went the other way, and the next hypothesis Phoenix can validate.

Research issue
Issue 01
Data through
2026-08-09
Evidence map version
v1.1.0
Explore the evidence Get the Evidence Map

How to read this

Phoenix research is longitudinal and observational: we follow real APOE4 carriers over time and compare each member with their own earlier self, with no placebo group, no randomisation, and members choosing their own interventions.

That means these are strong signals pointing at what to test next, not proof of cause. Most nutrition, supplement and lifestyle research you read online has exactly the same design. The difference is that we say so, and we show you the confounders.

Read the full methods and limits

What the Phoenix community is measuring

Browse exact outcomes and interventions. Each result keeps its source, measurement rule and audit record beside the claim.

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NMN evidence dossier

Evidence collected through 2026-08-09.

Most promising

LDL cholesterol

Laboratory LDL cholesterol result · Aim: lower

NMN

✓Positive individual result

One clean curated NMN case lowered LDL cholesterol 26.3% in 42 days; paired values were not published.

Selected member cases

  1. NMN LDL case · APOE3/4 · female · age 50-59

    LDL cholesterol fell 26.3% in a 42-day clean window; paired values were not printed.

    What else changed: no nearby starts were recorded.

    Next study: A small short product-specific human trial provides preliminary context, not a general NMN lipid verdict.

1 selected member case · not a response rate

Logged members
1
Members with repeats
1
Observations
1
Measurements
2
Sources and context

Members with a logged NMN start and repeat LDL result; the visible case is curated.

  • report-lines-248-343, reviewed by independent verifier

1 selected case shown with this evidence.

Not yet measured

A small short product-specific human trial provides preliminary context, not a general NMN lipid verdict.

How to test it

Baseline
Record LDL cholesterol before the dated NMN start.
Duration
84 days
Adherence
Record product, dose and adherence throughout the window.
Retest
Repeat LDL cholesterol after 12 weeks.
Falsifier
Clean NMN windows do not reproduce lower LDL cholesterol.
Eligible-member target
40 members
Keep the map

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Turn evidence into your next test

Magnesium and homocysteine is 7 members from an answer.

Forty carriers with a dated start and a repeat blood test close it. Creatine, vitamin D3 and B12 sit further back. Your next blood test is somebody else's answer, and theirs is yours.

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