Browse by exact outcome

Triglycerides: every measured intervention

Ranked only against the same measurement, in the same unit. See the positive, neutral, opposite-direction and still-collecting evidence before deciding what is worth your own test.

Phoenix APOE4 Research · Reviewed by Kevin Tran, APOE4/4 carrier and founder · Data through 2026-08-23 · How to read this research

How to read this

Observational research: real APOE4 carriers tracked over time, each compared with their own earlier self. Members chose their interventions, with no randomisation or placebo group. Everything else they changed is shown beside each result.

Read the full methods and limits

Questions about Triglycerides

What can improve Triglycerides for APOE4 carriers?

For APOE4 carriers, Phoenix has published positive evidence for Plain omega-3, Curcumin, Metformin, Niacin, Estradiol patch, Ezetimibe, Lysoveta DHA-LPC, Probiotics, Psyllium, and Statin family against Triglycerides. Member #1EA5B3's triglycerides moved from 64 to 40 mg/dL, down 37.5%, across a one-year clean window. Member #88F838's Triglycerides moved from 74 to 59 mg/dL in 100 days. Member #2351C3's Triglycerides moved from 101 to 62 mg/dL in 795 days. Member #4025C9's Triglycerides moved from 119 to 76 mg/dL in 255 days. Member #D9A2BF's triglycerides moved from 230 to 146 mg/dL, about 37% lower, across six months. Member #B50FCD's Triglycerides moved from 59.4 to 46.9 mg/dL in 85 days. Member #1EB8E9's Triglycerides moved from 81 to 52.3 mg/dL in 106 days. One clean curated case lowered triglycerides from 49 to 34 mg/dL in 59 days. Member #8DF8C2 lowered triglycerides from 70 to 40 mg/dL in the same 70-day window, with an estradiol patch active the full window alongside ezetimibe and Lysoveta. Member #5AA27F's longer statin arc also lowered triglycerides from 67 to 53 mg/dL, both already inside the normal range.

What has Phoenix measured against Triglycerides?

Phoenix has measured 10 interventions against Triglycerides: 10 positive. See the table below.

Every intervention measured against Triglycerides

Interventions measured against Triglycerides
InterventionWhat we observedEvidence status
Plain omega-3Member #1EA5B3's triglycerides moved from 64 to 40 mg/dL, down 37.5%, across a one-year clean window.Repeated positive
CurcuminMember #88F838's Triglycerides moved from 74 to 59 mg/dL in 100 days.Positive individual result
MetforminMember #2351C3's Triglycerides moved from 101 to 62 mg/dL in 795 days.Positive individual result
NiacinMember #4025C9's Triglycerides moved from 119 to 76 mg/dL in 255 days.Positive individual result
Estradiol patchMember #D9A2BF's triglycerides moved from 230 to 146 mg/dL, about 37% lower, across six months.Positive individual result
EzetimibeMember #B50FCD's Triglycerides moved from 59.4 to 46.9 mg/dL in 85 days.Positive individual result
Lysoveta DHA-LPCMember #1EB8E9's Triglycerides moved from 81 to 52.3 mg/dL in 106 days.Positive individual result
ProbioticsOne clean curated case lowered triglycerides from 49 to 34 mg/dL in 59 days.Positive individual result
PsylliumMember #8DF8C2 lowered triglycerides from 70 to 40 mg/dL in the same 70-day window, with an estradiol patch active the full window alongside ezetimibe and Lysoveta.Positive individual result
Statin familyMember #5AA27F's longer statin arc also lowered triglycerides from 67 to 53 mg/dL, both already inside the normal range.Positive individual result

What changed for real APOE4 carriers?

Search by health goal or intervention to see what changed for real members, including results that moved the wrong way.

Join Phoenix

Cholesterol and heart risk · Lower triglycerides · 10 interventions shown.

Health goalCholesterol and heart risk
SubgoalLower triglycerides

Lower triglycerides

Interventions tested: 10

Curcumin

SupplementsOutcomes: 1

Triglycerides: Decrease 15 mg/dL

Cases: 1

Details

Member #88F838's Triglycerides moved from 74 to 59 mg/dL in 100 days.

Curcumin

✓Positive individual result

Member #88F838's Triglycerides moved from 74 to 59 mg/dL in 100 days.

Selected member cases

  1. Phoenix memberAPOE4/450female

    Triglycerides

    Before74After59mg/dL-20.3%

    100 days between measurements

    Full stack credited: Curcumin (phospholipid complex) (lead), Lysoveta (DHA-LPC) (undated).

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Triglycerides after a dated Curcumin window.

logged members
1
members with repeats
1
observations
1
measurements
2

Full record

Estradiol patch

MedicationsOutcomes: 1

Triglycerides: Decrease 84 mg/dL

Cases: 1

Details

Member #D9A2BF's triglycerides moved from 230 to 146 mg/dL, about 37% lower, across six months.

Estradiol patch

✓Positive individual result

Member #D9A2BF's triglycerides moved from 230 to 146 mg/dL, about 37% lower, across six months.

Selected member cases

  1. Phoenix memberAPOE3/457female

    Triglycerides

    Before230After146mg/dL-36.5%

    179 days between measurements

    Full stack credited: Estradiol patch (lead), Estradiol transdermal gel (co), Omega-3 (undated), Progesterone (co).

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Triglycerides after a dated Estradiol patch window.

logged members
34
members with repeats
1
observations
1
measurements
2

Full record

Ezetimibe

MedicationsOutcomes: 1

Triglycerides: Decrease 12.5 mg/dL

Cases: 1

Details

Member #B50FCD's Triglycerides moved from 59.4 to 46.9 mg/dL in 85 days.

Ezetimibe

✓Positive individual result

Member #B50FCD's Triglycerides moved from 59.4 to 46.9 mg/dL in 85 days.

Selected member cases

  1. Phoenix memberAPOE4/458female

    Triglycerides

    Before59.4After46.9mg/dL-21%

    85 days between measurements

    Consistent with established evidence

    Full stack credited: Ezetimibe (lead), Lysoveta (DHA-LPC) (co).

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Triglycerides after a dated Ezetimibe window.

logged members
1
members with repeats
1
observations
1
measurements
2

Full record

Lysoveta DHA-LPC

SupplementsOutcomes: 1

Triglycerides: Decrease 28.7 mg/dL

Cases: 1

Details

Member #1EB8E9's Triglycerides moved from 81 to 52.3 mg/dL in 106 days.

Lysoveta DHA-LPC

✓Positive individual result

Member #1EB8E9's Triglycerides moved from 81 to 52.3 mg/dL in 106 days.

Selected member cases

  1. Phoenix memberAPOE4/457female

    Triglycerides

    Before81After52.3mg/dL-35.4%

    106 days between measurements

    Full stack credited: Lysoveta (DHA-LPC) (lead), Curcumin (co), Nicotinamide riboside (co).

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Triglycerides after a dated Lysoveta DHA-LPC window.

logged members
1
members with repeats
1
observations
1
measurements
2

Full record

Metformin

MedicationsOutcomes: 1

Triglycerides: Decrease 39 mg/dL

Cases: 1

Details

Member #2351C3's Triglycerides moved from 101 to 62 mg/dL in 795 days.

Metformin

✓Positive individual result

Member #2351C3's Triglycerides moved from 101 to 62 mg/dL in 795 days.

Selected member cases

  1. Phoenix memberAPOE4/456male

    Triglycerides

    Before101After62mg/dL-38.6%

    795 days between measurements

    Full stack credited: Metformin (lead), Omega-3 (co), Rosuvastatin (co), Ezetimibe (undated).

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Triglycerides after a dated Metformin window.

logged members
1
members with repeats
1
observations
1
measurements
2

Full record

Niacin

SupplementsOutcomes: 1

Triglycerides: Decrease 43 mg/dL

Cases: 1

Details

Member #4025C9's Triglycerides moved from 119 to 76 mg/dL in 255 days.

Niacin

✓Positive individual result

Member #4025C9's Triglycerides moved from 119 to 76 mg/dL in 255 days.

Selected member cases

  1. Phoenix memberAPOE4/456female

    Triglycerides

    Before119After76mg/dL-36.1%

    255 days between measurements

    Full stack credited: Niacin (lead), Niacinamide (co), Omega-3 (co), Curcumin (co).

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Triglycerides after a dated Niacin window.

logged members
1
members with repeats
1
observations
1
measurements
2

Full record

Plain omega-3

SupplementsOutcomes: 1

Triglycerides: Decrease 14–93 mg/dL

Cases: 5Case range

Details

Member #1EA5B3's triglycerides moved from 64 to 40 mg/dL, down 37.5%, across a one-year clean window.

Plain omega-3

✓Repeated positive

Member #1EA5B3's triglycerides moved from 64 to 40 mg/dL, down 37.5%, across a one-year clean window.

Selected member cases

  1. Phoenix memberAPOE3/458female

    Triglycerides

    Before62After48mg/dL-22.6%

    77 days between measurements

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Triglycerides after a dated Plain omega-3 window.

  2. Phoenix memberAPOE4/466male

    Triglycerides

    Before64After40mg/dL-37.5%

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Triglycerides after a dated Plain omega-3 window.

  3. Phoenix memberAPOE4/455female

    Triglycerides

    Before94After67mg/dL-28.7%

    216 days between measurements

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Triglycerides after a dated Plain omega-3 window.

  4. Phoenix memberAPOE4/455male

    Triglycerides

    Before154After61mg/dL-60.4%

    102 days between measurements

    Full stack credited: Omega-3 (lead), Statin (co).

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Triglycerides after a dated Plain omega-3 window.

  5. Phoenix memberAPOE4/454male

    Triglycerides

    Before98After71mg/dL-27.6%

    203 days between measurements

    Full stack credited: Omega-3 (lead), Statin (co), Tirzepatide (co), Curcumin (co).

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Triglycerides after a dated Plain omega-3 window.

logged members
159
members with repeats
4
observations
4
measurements
8

Full record

Probiotics

SupplementsOutcomes: 1

Triglycerides: Decrease 15 mg/dL

Cases: 1

Details

One clean curated case lowered triglycerides from 49 to 34 mg/dL in 59 days.

Probiotics

✓Positive individual result

One clean curated case lowered triglycerides from 49 to 34 mg/dL in 59 days.

Little published human data on this link yet.

Selected member cases

  1. Phoenix memberAPOE3/448female

    Triglycerides

    Before49After34mg/dL-30.6%

    59 days between measurements

    Full stack credited: Statin (lead), Probiotics (co), Berberine (undated), Lysoveta (DHA-LPC) (undated).

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Triglycerides after a dated Probiotics window.

observations
1
measurements
2

Full record

Psyllium

SupplementsOutcomes: 1

Triglycerides: Decrease 30 mg/dL

Cases: 1

Details

Member #8DF8C2 lowered triglycerides from 70 to 40 mg/dL in the same 70-day window, with an estradiol patch active the full window alongside ezetimibe and Lysoveta.

Psyllium

✓Positive individual result

Member #8DF8C2 lowered triglycerides from 70 to 40 mg/dL in the same 70-day window, with an estradiol patch active the full window alongside ezetimibe and Lysoveta.

Selected member cases

  1. Phoenix memberAPOE4/455female

    Triglycerides

    Before70After40mg/dL-42.9%

    70 days between measurements

    Full stack credited: Ezetimibe (lead), Lysoveta (DHA-LPC) (undated), Estradiol patch (co).

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Triglycerides after a dated Psyllium window.

logged members
1
members with repeats
1
observations
1
measurements
2

Full record

Statin family

MedicationsOutcomes: 1

Triglycerides: Decrease 14 mg/dL

Cases: 1

Details

Member #5AA27F's longer statin arc also lowered triglycerides from 67 to 53 mg/dL, both already inside the normal range.

Statin family

✓Positive individual result

Member #5AA27F's longer statin arc also lowered triglycerides from 67 to 53 mg/dL, both already inside the normal range.

Selected member cases

  1. Phoenix memberAPOE3/462female

    Triglycerides

    Before67After53mg/dL-20.9%

    353 days between measurements

    Full stack credited: Statin (lead), Citicoline (co), Omega-3 (undated), Lysoveta (DHA-LPC) (undated), Curcumin (undated), Estradiol patch (undated).

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Triglycerides after a dated Statin family window.

logged members
1
members with repeats
1
observations
1
measurements
2

Full record

The Beat the Odds Study

The 43-page study: what members tried, how their bloodwork and wearable results changed, and what else changed alongside them.

Download the Beat the Odds Study

Turn evidence into your next test

I built this so nobody has to be the first to try something.

476 members have already tried, measured and logged. Join Phoenix and your next blood draw joins the same Navigator you are reading.

Join Phoenix