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Phoenix APOE4 Research · Reviewed by Kevin Tran, APOE4/4 carrier and founder · Data through 2026-08-23 · How to read this research
How to read this
Observational research: real APOE4 carriers tracked over time, each compared with their own earlier self. Members chose their interventions, with no randomisation or placebo group. Everything else they changed is shown beside each result.
Read the full methods and limitsPhoenix has measured Magnesium glycinate against 3 exact outcomes for APOE4 carriers. Member #EFF528's Glucose moved from 97 to 88 mg/dL in 338 days. Member #EFF528's HbA1c moved from 5.7 to 5.1 % in 338 days. Member #EFF528's Homocysteine moved from 7 to 6 µmol/L in 207 days.
| Outcome | Direction | What we observed |
|---|---|---|
| Glucose | Repeated positive | Member #EFF528's Glucose moved from 97 to 88 mg/dL in 338 days. |
| HbA1c | Positive individual result | Member #EFF528's HbA1c moved from 5.7 to 5.1 % in 338 days. |
| Homocysteine | Repeated positive | Member #EFF528's Homocysteine moved from 7 to 6 µmol/L in 207 days. |
Phoenix has measured Magnesium glycinate against 3 exact outcomes for APOE4 carriers. Member #EFF528's Glucose moved from 97 to 88 mg/dL in 338 days. Member #EFF528's HbA1c moved from 5.7 to 5.1 % in 338 days. Member #EFF528's Homocysteine moved from 7 to 6 µmol/L in 207 days.
Member #EFF528's Glucose moved from 97 to 88 mg/dL in 338 days. Support: 4 logged members, 4 members with repeats, 4 observations, 8 measurements.
Member #EFF528's HbA1c moved from 5.7 to 5.1 % in 338 days. Support: 1 logged members, 1 members with repeats, 1 observations, 2 measurements.
Member #EFF528's Homocysteine moved from 7 to 6 µmol/L in 207 days. Support: 2 logged members, 2 members with repeats, 2 observations, 4 measurements.
Search by health goal or intervention to see what changed for real members, including results that moved the wrong way.
Magnesium glycinate · 3 outcomes shown.
Glucose: Decrease 7–13.7 mg/dL
Cases: 4Case range
Member #EFF528's Glucose moved from 97 to 88 mg/dL in 338 days.
Magnesium glycinate
✓Repeated positiveMember #EFF528's Glucose moved from 97 to 88 mg/dL in 338 days.
Glucose
Before86After76mg/dL-11.6%
110 days between measurements
Mixed or inconclusive
Full stack credited: Magnesium Glycinate (lead), CoQ10 (co).
Since this result, glucose climbed back to 86 mg/dL and then 89 mg/dL, at or above the original starting point, in the draws closest to Phoenix's data freeze. The printed drop reflects a single low reading that did not hold.
What else changed: no nearby starts were recorded.
Next study: repeat Glucose after a dated Magnesium glycinate window.
Glucose
Before97After88mg/dL-9.3%
338 days between measurements
What else changed: no nearby starts were recorded.
Next study: repeat Glucose after a dated Magnesium glycinate window.
Glucose
Before98.7After85mg/dL-13.9%
70 days between measurements
Full stack credited: Magnesium Glycinate (lead), Tirzepatide (co).
What else changed: no nearby starts were recorded.
Next study: repeat Glucose after a dated Magnesium glycinate window.
Glucose
Before87After80mg/dL-8%
68 days between measurements
Full stack credited: Magnesium Glycinate (undated), CoQ10 (lead), Ubiquinol (undated).
What else changed: no nearby starts were recorded.
Next study: repeat Glucose after a dated Magnesium glycinate window.
HbA1c: Decrease 0.6 %
Cases: 1
Member #EFF528's HbA1c moved from 5.7 to 5.1 % in 338 days.
Magnesium glycinate
✓Positive individual resultMember #EFF528's HbA1c moved from 5.7 to 5.1 % in 338 days.
HbA1c
Before5.7After5.1%-0.6 percentage points
338 days between measurements
What else changed: no nearby starts were recorded.
Next study: repeat HbA1c after a dated Magnesium glycinate window.
Homocysteine: Decrease 1.0–2.0 µmol/L
Cases: 2Case range
Member #EFF528's Homocysteine moved from 7 to 6 µmol/L in 207 days.
Magnesium glycinate
✓Repeated positiveMember #EFF528's Homocysteine moved from 7 to 6 µmol/L in 207 days.
Homocysteine
Before7.3After5.3µmol/L-27.4%
196 days between measurements
Full stack credited: Magnesium Glycinate (lead), Vitamin B12 (undated).
What else changed: no nearby starts were recorded.
Next study: repeat Homocysteine after a dated Magnesium glycinate window.
Homocysteine
Before7.0After6.0µmol/L-14.3%
207 days between measurements
Full stack credited: Magnesium Glycinate (lead), B Complex (co).
What else changed: no nearby starts were recorded.
Next study: repeat Homocysteine after a dated Magnesium glycinate window.
The 43-page study: what members tried, how their bloodwork and wearable results changed, and what else changed alongside them.
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