Ranked only against the same measurement, in the same unit. See the positive, neutral, opposite-direction and still-collecting evidence before deciding what is worth your own test.
Phoenix APOE4 Research · Reviewed by Kevin Tran, APOE4/4 carrier and founder · Data through 2026-08-23 · How to read this research
How to read this
Observational research: real APOE4 carriers tracked over time, each compared with their own earlier self. Members chose their interventions, with no randomisation or placebo group. Everything else they changed is shown beside each result.
Read the full methods and limitsFor APOE4 carriers, Phoenix has published positive evidence for Magnesium threonate and Magnesium glycinate against HbA1c. The same two magnesium-threonate cases nudged HbA1c lower, but the public engine does not publish their before-and-after values. Member #EFF528's HbA1c moved from 5.7 to 5.1 % in 338 days.
Phoenix has measured 2 interventions against HbA1c: 2 positive. See the table below.
| Intervention | What we observed | Evidence status |
|---|---|---|
| Magnesium threonate | The same two magnesium-threonate cases nudged HbA1c lower, but the public engine does not publish their before-and-after values. | Positive individual result |
| Magnesium glycinate | Member #EFF528's HbA1c moved from 5.7 to 5.1 % in 338 days. | Positive individual result |
Search by health goal or intervention to see what changed for real members, including results that moved the wrong way.
Blood sugar · Lower HbA1c · 2 interventions shown.
HbA1c: Decrease 0.6 %
Cases: 1
Member #EFF528's HbA1c moved from 5.7 to 5.1 % in 338 days.
Magnesium glycinate
✓Positive individual resultMember #EFF528's HbA1c moved from 5.7 to 5.1 % in 338 days.
HbA1c
Before5.7After5.1%-0.6 percentage points
338 days between measurements
What else changed: no nearby starts were recorded.
Next study: repeat HbA1c after a dated Magnesium glycinate window.
HbA1c: Decrease
Cases: 2
The same two magnesium-threonate cases nudged HbA1c lower, but the public engine does not publish their before-and-after values.
Magnesium threonate
✓Positive individual resultThe same two magnesium-threonate cases nudged HbA1c lower, but the public engine does not publish their before-and-after values.
Little published human data on this link yet.
HbA1c moved lower in the same clean window; public before-and-after values were not printed.
What else changed: nearby starts included B-vitamin intake not captured.
Next study: repeat HbA1c after a dated Magnesium threonate window.
This result is under review: Not published alongside the homocysteine finding above: magnesium threonate has only 6 days of confirmed exposure before the after-draw in a much longer window.
The 43-page study: what members tried, how their bloodwork and wearable results changed, and what else changed alongside them.
Turn evidence into your next test
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Choose an outcome, like LDL cholesterol or sleep, or an intervention, like training: both paths open the same measured records.