Browse by exact outcome

HDL cholesterol: every measured intervention

Ranked only against the same measurement, in the same unit. See the positive, neutral, opposite-direction and still-collecting evidence before deciding what is worth your own test.

Research issue
Issue 01
Data through
2026-08-09
Evidence map version
v1.1.0
Explore the evidence Get the Evidence Map

How to read this

Phoenix research is longitudinal and observational: we follow real APOE4 carriers over time and compare each member with their own earlier self, with no placebo group, no randomisation, and members choosing their own interventions.

That means these are strong signals pointing at what to test next, not proof of cause. Most nutrition, supplement and lifestyle research you read online has exactly the same design. The difference is that we say so, and we show you the confounders.

Read the full methods and limits

What the Phoenix community is measuring

Browse exact outcomes and interventions. Each result keeps its source, measurement rule and audit record beside the claim.

Get the PDFJoin Phoenix in 7 minutes Open inside Phoenix

Cholesterol and heart risk

Keep LDL, ApoB, HDL, triglycerides and other lipid outcomes separate.

Most promising

HDL cholesterol

Laboratory HDL cholesterol result · Aim: higher

Lysoveta DHA-LPC

✓Repeated positive

Two clean curated cases raised HDL cholesterol by 18.7% and 11.5%; external literature does not establish this Lysoveta lipid effect.

Selected member cases

  1. Lysoveta HDL case two · genotype not disclosed · female · age not disclosed

    HDL cholesterol rose 11.5% in a second clean window; paired values and elapsed days were not printed.

    What else changed: no nearby starts were recorded.

    Next study: repeat HDL cholesterol after a dated Lysoveta DHA-LPC window.

  2. Omega Lifter · APOE4/4 · male · age 40-49

    61.5 → 73 mg/dL · +18.7% · 67 days

    What else changed: no nearby starts were recorded.

    Next study: repeat HDL cholesterol after a dated Lysoveta DHA-LPC window.

2 selected member cases · not a response rate

Logged members
2
Members with repeats
2
Observations
2
Measurements
4
Sources and context

Members with a logged Lysoveta start and repeat HDL cholesterol result; visible cases are curated.

  • report-lines-248-343, reviewed by independent verifier

2 selected cases shown with this evidence.

Butyrate

✓Positive individual result

One curated butyrate case raised HDL cholesterol 32.5% in 85 days; paired values were not published.

Selected member cases

  1. Butyrate HDL case · APOE4/4 · female · age 50-59

    HDL cholesterol rose 32.5% in an 85-day clean window; paired values were not printed.

    What else changed: no nearby starts were recorded.

    Next study: repeat HDL cholesterol after a dated Butyrate window.

1 selected member case · not a response rate

Logged members
1
Members with repeats
1
Observations
1
Measurements
2
Sources and context

Members with a logged butyrate start and repeat HDL cholesterol result; the visible case is curated.

  • report-lines-248-343, reviewed by independent verifier

1 selected case shown with this evidence.

Estradiol patch

✓Positive individual result

The Night Shift's HDL cholesterol moved from 32 to 41 mg/dL, about 28% higher, across six months.

Selected member cases

  1. Night Shift · APOE3/4 · female · age 50-59

    HDL cholesterol rose from 32 to 41 mg/dL across six months; exact elapsed days were not printed.

    What else changed: no nearby starts were recorded.

    Next study: repeat HDL cholesterol after a dated Estradiol patch window.

1 selected member case · not a response rate

Logged members
34
Members with repeats
1
Observations
1
Measurements
2
Sources and context

Curated estradiol-patch cases with repeat HDL cholesterol; broader estradiol-form users are support context only.

  • report-lines-215-245, reviewed by independent verifier

1 selected case shown with this evidence.

Lithium orotate

✓Positive individual result

One curated lithium-orotate case raised HDL cholesterol 24%; the report prints no paired values or elapsed days.

Selected member cases

  1. Lithium HDL case · genotype not disclosed · sex not disclosed · age not disclosed

    HDL cholesterol rose 24%; paired values and elapsed days were not printed.

    What else changed: no nearby starts were recorded.

    Next study: repeat HDL cholesterol after a dated Lithium orotate window.

1 selected member case · not a response rate

Logged members
77
Members with repeats
1
Observations
1
Measurements
2
Sources and context

Curated lithium-orotate cases with a named repeat lipid outcome.

  • report-lines-248-343, reviewed by independent verifier

1 selected case shown with this evidence.

Keep the map

Take every result into your next experiment.

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Turn evidence into your next test

Magnesium and homocysteine is 7 members from an answer.

Forty carriers with a dated start and a repeat blood test close it. Creatine, vitamin D3 and B12 sit further back. Your next blood test is somebody else's answer, and theirs is yours.

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