Metformin: what it changed, and what it did not

One curated case had 134 more deep-plus-REM minutes; the 11-member ten-tag-day cohort averaged about 17 more minutes and stayed positive at every floor.

Little published human data on this link yet.

logged members

19

members with repeats

11

observations

1

Two curated earlier-bedtime cases carried part of their longer sleep in deep plus REM stages; exact group-stage counts are not published.

observations

2

nights

53

Two curated ZenoWell cases carried 44 and 23 more deep-plus-REM minutes on use nights; five of 40 study members had valid wearable coverage.

Little published human data on this link yet.

logged members

40

members with repeats

5

observations

2

nights

228

measurements

228

Among APOE4/4 carriers logging early bedtime, better subjective sleep ratings outnumbered worse ratings; no public responder percentage is generated.

logged members

60

members with repeats

60

Member #6D3F21's Mediterranean-keto days averaged 1.3 sleep-quality points higher.

Little published human data on this link yet.

logged members

1

members with repeats

1

observations

1

Member #CBC9E3 rated sleep 7.8 on sauna days versus 5.8 on comparison days, a 2.1-point advantage after rounding.

Little published human data on this link yet.

logged members

1

members with repeats

1

observations

114

measurements

114

Two analyses found earlier nights about 30 minutes longer: 56 of 68 eligible members under one rule and 59 of 66 eligible members under a stricter rule. No blended response rate is published.

observations

2

nights

53

Member #25E479 averaged 522 total sleep minutes on use nights versus 494 on comparison nights across 77 nights.

Little published human data on this link yet.

logged members

40

members with repeats

5

observations

1

nights

77

measurements

77

One curated member rated morning-caffeine sleep lower while another felt no change despite a wearable-stage decline.

logged members

2

members with repeats

2

observations

2

Untimed caffeine and coffee tags showed no deep-plus-REM pattern, unlike the explicitly timed morning-caffeine tag.

Sleep regularity did not outperform sleep duration on any matched-night definition tested in the published Phoenix evidence.

Little published human data on this link yet.

Deep plus REM sleep was 3 minutes lower at one tagged day and 8 minutes lower among 24 members with at least ten tagged days.

logged members

43

members with repeats

24

observations

2

Across 32 members with at least ten workout tags, workout nights averaged about 11 fewer deep-plus-REM minutes.

Little published human data on this link yet.

logged members

32

members with repeats

32

Member #B2E9BC's same-night deep sleep was 30% to 35% lower across two computations.

Little published human data on this link yet.

logged members

1

members with repeats

1

observations

1

External-stress weeks averaged 1.3 sleep-quality points lower; only a handful of dense loggers contributed.

Travel weeks averaged 1.7 sleep-quality points lower; only a handful of dense loggers contributed.

Member #6D3F21's drinking nights averaged 1.72 sleep-quality points lower across 25 drinking and 35 comparison nights.

logged members

1

members with repeats

1

observations

60

nights

60

measurements

60

Member #2351C3's Glucose moved from 114 to 88 mg/dL in 718 days.

logged members

1

members with repeats

1

observations

1

measurements

2

Member #15000A lowered fasting insulin from 12.6 to 6.5 uIU/mL in 162 days on metformin and tirzepatide, both undated.

logged members

1

members with repeats

1

observations

1

measurements

2

Member #2351C3's LDL cholesterol moved from 83 to 59 mg/dL in 881 days.

logged members

1

members with repeats

1

observations

1

measurements

2

Member #2351C3's Triglycerides moved from 101 to 62 mg/dL in 795 days.

logged members

1

members with repeats

1

observations

1

measurements

2