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Phoenix APOE4 Research · Reviewed by Kevin Tran, APOE4/4 carrier and founder · Data through 2026-08-23 · How to read this research
How to read this
Observational research: real APOE4 carriers tracked over time, each compared with their own earlier self. Members chose their interventions, with no randomisation or placebo group. Everything else they changed is shown beside each result.
Read the full methods and limitsPhoenix has measured Training and workouts against 3 exact outcomes for APOE4 carriers. Across 32 members with at least ten workout tags, workout nights averaged about 11 fewer deep-plus-REM minutes. Member #B2E9BC's same-night deep sleep was 30% to 35% lower across two computations. Member #B2E9BC's next-day HRV was 29% to 32% higher across two computations. A separate case was not published as a finding.
| Outcome | Direction | What we observed |
|---|---|---|
| Deep plus REM sleep | Opposite direction | Across 32 members with at least ten workout tags, workout nights averaged about 11 fewer deep-plus-REM minutes. |
| Deep sleep | Opposite direction | Member #B2E9BC's same-night deep sleep was 30% to 35% lower across two computations. |
| Heart-rate variability | Positive individual result | Member #B2E9BC's next-day HRV was 29% to 32% higher across two computations. A separate case was not published as a finding. |
Phoenix has measured Training and workouts against 3 exact outcomes for APOE4 carriers. Across 32 members with at least ten workout tags, workout nights averaged about 11 fewer deep-plus-REM minutes. Member #B2E9BC's same-night deep sleep was 30% to 35% lower across two computations. Member #B2E9BC's next-day HRV was 29% to 32% higher across two computations. A separate case was not published as a finding.
Across 32 members with at least ten workout tags, workout nights averaged about 11 fewer deep-plus-REM minutes. Support: 32 logged members, 32 members with repeats.
Member #B2E9BC's same-night deep sleep was 30% to 35% lower across two computations. Support: 1 logged members, 1 members with repeats, 1 observations.
Member #B2E9BC's next-day HRV was 29% to 32% higher across two computations. A separate case was not published as a finding. Support: 1 logged members, 1 members with repeats, 1 observations.
Search by health goal or intervention to see what changed for real members, including results that moved the wrong way.
Training and workouts · 3 outcomes shown.
Deep + REM sleep: Decrease 11 min
Repeat members: 32Average
Across 32 members with at least ten workout tags, workout nights averaged about 11 fewer deep-plus-REM minutes.
Training and workouts
↘Opposite directionAcross 32 members with at least ten workout tags, workout nights averaged about 11 fewer deep-plus-REM minutes.
Little published human data on this link yet.
This result was not published as a finding: The plus-42-minute workout line did not meet the independent recomputation standard and was not published as a finding.
Deep sleep: Decrease 30–35 %
Cases: 1
Member #B2E9BC's same-night deep sleep was 30% to 35% lower across two computations.
Training and workouts
↘Opposite directionMember #B2E9BC's same-night deep sleep was 30% to 35% lower across two computations.
Little published human data on this link yet.
Same-night deep sleep was 30% to 35% lower across two independent computations.
What else changed: no nearby starts were recorded.
Next study: repeat Deep sleep after a dated Training and workouts window.
Heart-rate variability: Increase 30.5 %
Cases: 1
Member #B2E9BC's next-day HRV was 29% to 32% higher across two computations. A separate case was not published as a finding.
Training and workouts
✓Positive individual resultMember #B2E9BC's next-day HRV was 29% to 32% higher across two computations. A separate case was not published as a finding.
Next-day HRV was 29% to 32% higher across two independent computations.
What else changed: no nearby starts were recorded.
Next study: repeat Heart-rate variability after a dated Training and workouts window.
This result was not published as a finding: A different July case did not meet Phoenix’s review standard.
The 43-page study: what members tried, how their bloodwork and wearable results changed, and what else changed alongside them.
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