Browse by exact outcome

Apolipoprotein B: every measured intervention

Ranked only against the same measurement, in the same unit. See the positive, neutral, opposite-direction and still-collecting evidence before deciding what is worth your own test.

Research issue
Issue 01
Data through
2026-08-09
Evidence map version
v1.1.0

How to read this

Phoenix research is longitudinal and observational: we follow real APOE4 carriers over time and compare each member with their own earlier self, with no placebo group, no randomisation, and members choosing their own interventions.

That means these are strong signals pointing at what to test next, not proof of cause. Most nutrition, supplement and lifestyle research you read online has exactly the same design. The difference is that we say so, and we show you the confounders.

Read the full methods and limits

What the Phoenix community is measuring

Browse exact outcomes and interventions. Each result keeps its source, measurement rule and audit record beside the claim.

Cholesterol and heart risk

Keep LDL, ApoB, HDL, triglycerides and other lipid outcomes separate.

Most promising

Apolipoprotein B

Laboratory apolipoprotein B result · Aim: lower

Creatine monohydrate

Positive individual result

The Fine Tuner later recorded a clean 12.3% ApoB reduction; Issue 01 does not print the paired values or elapsed days.

Selected member cases

  1. Fine Tuner · APOE3/4 · female · age 50-59

    ApoB fell 12.3% in a later clean creatine window; paired values and elapsed days were not printed.

    What else changed: no nearby starts were recorded.

    Next study: repeat Apolipoprotein B after a dated Creatine monohydrate window.

1 selected member case · not a response rate

Logged members
119
Members with repeats
1
Observations
1
Measurements
2
Sources and context

Members with a logged creatine start and repeat ApoB result; the visible case is curated.

  • report-lines-248-343, reviewed by independent verifier

1 selected case shown with this evidence.

Statin family

Positive individual result

The ApoB Ace lowered ApoB from 98 to 59 mg/dL in 77 days; generic and named statin use counts are not summed.

Selected member cases

  1. ApoB Ace · APOE3/4 · female · age 60-69

    98 → 59 mg/dL · -39.8% · 77 days

    What else changed: no nearby starts were recorded.

    Next study: repeat Apolipoprotein B after a dated Statin family window.

1 selected member case · not a response rate

Logged members
1
Members with repeats
1
Observations
1
Measurements
2
Sources and context

Curated statin-family cases with a dated start and repeat ApoB result.

  • report-lines-215-245, reviewed by independent verifier

1 selected case shown with this evidence.

Vitamin C

Positive individual result

The Monthly Retester's ApoB moved from 135 to 110 mg/dL in 39 days; deterministic arithmetic gives a reduction of 18.5%.

Selected member cases

  1. Monthly Retester · APOE4/4 · female · age 50-59

    135 → 110 mg/dL · -18.5% · 39 days

    What else changed: no nearby starts were recorded.

    Next study: Human trial synthesis did not establish an overall lipid effect or ApoB result, so the Phoenix case needs replication.

1 selected member case · not a response rate

Observations
1
Measurements
2
Sources and context

Members with a logged vitamin C start and repeat ApoB result; the visible case is curated.

  • report-lines-248-343, reviewed by independent verifier

1 selected case shown with this evidence.

Not yet measured

Human trial synthesis did not establish an overall lipid effect or ApoB result, so the Phoenix case needs replication.

How to test it

Baseline
Record ApoB before the dated vitamin C start.
Duration
84 days
Adherence
Record dose and adherence throughout the window.
Retest
Repeat ApoB after 12 weeks.
Falsifier
Clean vitamin C windows do not reproduce lower ApoB.
Eligible-member target
40 members
Keep the map

Take every result into your next experiment.

Get the Issue 01 Evidence Map by email. It groups the same evidence by outcome and by intervention, including what worked, what did not, and what Phoenix wants to test next.

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Turn evidence into your next test

Magnesium and homocysteine is 7 members from an answer.

Forty carriers with a dated start and a repeat blood test close it. Creatine, vitamin D3 and B12 sit further back. Your next blood test is somebody else's answer, and theirs is yours.

Take the 7-minute assessment