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Cholesterol and heart risk: what moved for Phoenix members

Keep LDL, ApoB, HDL, triglycerides and other lipid outcomes separate. Compare the interventions attached to each exact measurement before choosing what to test in yourself.

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Observational research: real APOE4 carriers tracked over time, each compared with their own earlier self. Members chose their interventions, with no randomisation or placebo group. Everything else they changed is shown beside each result.

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What changed for real APOE4 carriers?

Search by health goal or intervention to see what changed for real members, including results that moved the wrong way.

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Cholesterol and heart risk · Lower ApoB · 5 interventions shown.

Health goalCholesterol and heart risk
SubgoalLower ApoB

Lower ApoB

Interventions tested: 5

Ezetimibe

MedicationsOutcomes: 1

Apolipoprotein B: Decrease 36–41 mg/dL

Cases: 2Case range

Details

Member #29E727 lowered ApoB from 131 to 90 mg/dL in 133 days on an ezetimibe-led combination.

Ezetimibe

✓Repeated positive

Member #29E727 lowered ApoB from 131 to 90 mg/dL in 133 days on an ezetimibe-led combination.

Selected member cases

  1. Phoenix memberAPOE4/467female

    Apolipoprotein B

    Before131After90mg/dL-31.3%

    133 days between measurements

    Full stack credited: Ezetimibe (lead), Psyllium (co).

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Apolipoprotein B after a dated Ezetimibe window.

  2. Phoenix memberAPOE3/451female

    Apolipoprotein B

    Before147After111mg/dL-24.5%

    207 days between measurements

    Full stack credited: Ezetimibe (lead), Berberine (co).

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Apolipoprotein B after a dated Ezetimibe window.

logged members
2
members with repeats
2
observations
2
measurements
4

Full record

Probiotics

SupplementsOutcomes: 1

Apolipoprotein B: Decrease 25.2–27.9 mg/dL

Cases: 2Case range

Details

Member #1EB8E9's Apolipoprotein B moved from 122 to 94.1 mg/dL in 106 days.

Probiotics

✓Repeated positive

Member #1EB8E9's Apolipoprotein B moved from 122 to 94.1 mg/dL in 106 days.

Selected member cases

  1. Phoenix memberAPOE4/457female

    Apolipoprotein B

    Before135.2After110mg/dL-18.6%

    39 days between measurements

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Apolipoprotein B after a dated Probiotics window.

  2. Phoenix memberAPOE4/457female

    Apolipoprotein B

    Before122After94.1mg/dL-22.9%

    106 days between measurements

    Full stack credited: Probiotics (lead), Bergamot (co).

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Apolipoprotein B after a dated Probiotics window.

logged members
2
members with repeats
2
observations
2
measurements
4

Full record

Psyllium

SupplementsOutcomes: 1

Apolipoprotein B: Decrease 12 mg/dL

Cases: 1

Details

Member #61477B's Apolipoprotein B moved from 107 to 95 mg/dL in 115 days.

Psyllium

✓Positive individual result

Member #61477B's Apolipoprotein B moved from 107 to 95 mg/dL in 115 days.

Selected member cases

  1. Phoenix memberAPOE4/464female

    Apolipoprotein B

    Before107After95mg/dL-11.2%

    115 days between measurements

    Mixed or inconclusive

    Full stack credited: Psyllium (lead), Omega-3 (co).

    Since this result, ApoB was unchanged at the next draw, then climbed back to 104 mg/dL, close to the 107 mg/dL starting point, in the draw closest to Phoenix's data freeze.

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Apolipoprotein B after a dated Psyllium window.

logged members
1
members with repeats
1
observations
1
measurements
2

Full record

Statin family

MedicationsOutcomes: 1

Apolipoprotein B: Decrease 8–39 mg/dL

Cases: 2Case range

Details

Member #5AA27F lowered ApoB from 98 to 59 mg/dL in 77 days; generic and named statin use counts are not summed.

Statin family

✓Repeated positive

Member #5AA27F lowered ApoB from 98 to 59 mg/dL in 77 days; generic and named statin use counts are not summed.

Selected member cases

  1. Phoenix memberAPOE3/462female

    Apolipoprotein B

    Before98After59mg/dL-39.8%

    112 days between measurements

    Full stack credited: Statin (lead), Citicoline (co).

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Apolipoprotein B after a dated Statin family window.

  2. Phoenix memberAPOE4/454male

    Apolipoprotein B

    Before69After61mg/dL-11.6%

    203 days between measurements

    Full stack credited: Statin (lead), Probiotics (co).

    What else changed and what to test next

    What else changed: no nearby starts were recorded.

    Next study: repeat Apolipoprotein B after a dated Statin family window.

logged members
2
members with repeats
2
observations
2
measurements
4

Full record

Vitamin C

SupplementsOutcomes: 1

Apolipoprotein B: Decrease 18.5 %

Cases: 1

Context affected

Details

Member #1EB8E9's ApoB moved from 135 to 110 mg/dL in 39 days; deterministic arithmetic gives a reduction of 18.5%.

Vitamin C

?Collecting evidence

Member #1EB8E9's ApoB moved from 135 to 110 mg/dL in 39 days; deterministic arithmetic gives a reduction of 18.5%.

Not explained by the science yetVitamin C has no established mechanism for lowering ApoB particle count, and human RCTs on vitamin C and lipids are mostly null or mixed.

observations
1
measurements
2

Collecting evidence

No answer yet on Apolipoprotein B

Vitamin C is being tracked against Apolipoprotein B, but Phoenix has not yet published a ranked result for this exact question.

Every carrier who logs a dated start and a repeat test moves this page closer to an answer, including you.

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Context affected this result: Not printed as of Release 001: no ApoB-lowering mechanism for vitamin C, and the member's window carries six simultaneous starts with a real statin-class rival (rosuvastatin). This case is not included in the printed cases or test-next list.

Full record

The Beat the Odds Study

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