Trials in Kansas.

This trial tested bapineuzumab, an infused antibody designed to bind and clear beta amyloid from the brain, against a placebo. It measured whether it helped…

This trial tested whether bapineuzumab, an antibody given by infusion that helps clear beta amyloid from the brain, could affect thinking and daily function in…

This Phase 2 trial tested lecanemab, an anti-amyloid antibody given by infusion, in people with early Alzheimer's disease — either mild cognitive impairment or…

This trial tested two investigational drugs, CAD106 (a vaccine-like immunotherapy targeting amyloid) and CNP520 (a small molecule targeting amyloid…

This trial tested CNP520, a drug designed to reduce amyloid buildup in the brain, against a placebo in cognitively normal older adults at elevated risk for…

This Phase 3 trial tests lecanemab, an intravenous and subcutaneous antibody drug, against placebo in people with early Alzheimer's disease — either mild…

This trial is testing how a single session of moderate aerobic exercise changes brain blood flow and blood biomarkers in older adults who carry the APOE4 gene.…

This Phase 3 trial is testing lecanemab, an anti-amyloid antibody drug, in people who are cognitively normal but have early amyloid buildup in their brains —…

This trial tested bapineuzumab, an antibody drug given by infusion, against a placebo in people with mild to moderate Alzheimer's. It looked at how well the…

This trial tested bapineuzumab, an antibody drug given by infusion, against a placebo in people with mild to moderate Alzheimer's. Researchers measured safety…

Enroll-HD is an observational study, meaning no drug or treatment is given. It follows people with Huntington's disease, and their relatives and controls,…

This Phase 3 trial tested solanezumab, an antibody drug given by IV infusion, in cognitively normal older adults who already had amyloid buildup in their…

This is an observational study, so nothing is being tested as a treatment. Researchers are looking at how the genes and symptoms of ALS and related conditions,…

This trial tests whether aerobic exercise (like treadmill walking) does more for brain health than stretching and balance routines in older adults with mild…

This Phase 3 trial tested whether LCZ696 (sacubitril/valsartan, sold as Entresto) protects cognitive function better than valsartan alone in people with a…

This study is not testing a treatment. It is an observational study tracking how people with early-stage Alzheimer's disease or MCI use health care, what that…

This Phase 3 trial is testing whether escitalopram, a common antidepressant, can safely reduce agitation in people who already have Alzheimer's dementia. Phase…

This study uses information already in the medical records of people with ALS and related conditions to learn more about those diseases. It tests no drug or…

This is an observational study, not a drug test. It collects biological fluid samples, such as blood, from people with ALS and related conditions, plus healthy…

This trial is testing whether a single IV infusion of zoledronic acid, a bone-strengthening drug already approved for osteoporosis, can reduce fractures in…

This trial is testing whether Cognitive Behavioral Therapy for Insomnia (CBT-I) — a structured, talk-based sleep program — can improve memory and thinking…

This trial is testing whether extended-release metformin, a widely used diabetes drug, can slow memory decline in people who are overweight and already showing…

This is not a treatment trial. It is a study building a pool of adults with Down syndrome, ages 25 to 55, who are ready to be recruited into future Alzheimer's…

PREVENTABLE is a large Phase 4 trial testing whether atorvastatin 40 mg — a common cholesterol-lowering statin — can reduce the combined risk of death,…

This Phase 3 trial tested donanemab, an anti-amyloid antibody drug, against placebo in people with early Alzheimer's disease. Researchers measured how well it…

This trial is testing an online training program called CHATO that teaches nursing home staff how to communicate better with residents who have dementia. The…

This is an observational study, meaning no drug or treatment is given. Researchers are looking at people with ALS and related conditions, including…

This trial tests donanemab, an anti-amyloid antibody given by infusion, against a placebo in people with no memory or thinking problems but signs of amyloid in…

This trial tests ACI-24.060, an active vaccine-style treatment meant to prompt the body to make its own antibodies against amyloid, a sticky protein linked to…

This Phase 3 trial is testing remternetug, an anti-amyloid antibody given by IV or injection under the skin, in people with early symptomatic Alzheimer's…

This trial is testing whether weight loss through a reduced-calorie diet can help protect the brains of adults with Down syndrome who do not yet have dementia.…

This trial tests a skin patch containing dexmedetomidine, a sedating medication, to see if it reduces how often and how severe agitation is in people with…

This study tests whether guided mental imagery, like picturing your future self enjoying exercise, makes mid-life adults more excited about working out and…

This trial tests remternetug, an anti-amyloid antibody drug, against a placebo. It measures how long it takes for memory, thinking, or daily-function problems…

This trial is testing whether a smartphone app can deliver personalized exercise programs to sedentary adults in rural Kansas and improve health markers tied…

This trial tests whether buntanetap, a daily pill, slows memory and thinking decline and helps everyday function in adults 55 to 85 with early Alzheimer's. It…

This trial tests CuidaTEXT, a text message program for Latino family caregivers of people with Alzheimer's or related dementias. Researchers want to see…

This Phase 2 trial is testing LHP588, an oral capsule taken once daily, in people with mild to moderate Alzheimer's disease who also test positive for P.…

This trial tests ONO-2020, an experimental pill that works on gene regulation, in people already diagnosed with mild to moderate Alzheimer's. Researchers want…

This trial is testing whether a drug called ACP-204 reduces hallucinations and delusions in people with Lewy body dementia or Parkinson's disease dementia,…

This trial is testing VHB937, a biological drug, in people with early Alzheimer's disease — either mild cognitive impairment or mild AD confirmed by…

This trial follows people with Lewy body dementia who experience psychosis, such as hallucinations or delusions. It tests an experimental drug, ACP-204, taken…

This trial is testing votoplam, an oral drug designed to slow the progression of early-stage Huntington's disease. Researchers are comparing it against a…

This trial is testing whether a ketogenic diet can reduce joint pain and improve physical function and cognition in adults who have both osteoarthritis and…

This trial is testing a remote exercise and caregiver education program adapted for older adults with Down syndrome, who face a very high lifetime risk of…

This trial tests whether donanemab, an anti-amyloid antibody given by infusion, slows the decline in thinking and daily function compared with a placebo. It…

This trial tests whether a drug called pridopidine can slow the worsening of Huntington's disease over one year, compared with a placebo. It looks at movement,…