Welcome from Sequencing.com

For readers arriving from a Sequencing.com APOE4 report

You just found out. Start with one clear next step.

Phoenix is an app and community for APOE4 carriers. Bring your questions and the health information you already have.

An APOE4 result tells you about genetic risk. It is not an Alzheimer’s diagnosis.

Apply to join Phoenix Read the free first 7 days guide

60-day money-back guarantee

Use code SEQUENCING at checkout for 10% off your membership.

Your home for everything APOE4.

As seen in

See what worked for carriers like you.
Then validate that it works for you.

What works for carriers like you is more likely to work for you.
Your own results then show whether it does.

1Carriers like you went first

A better starting point for your next step.

Compare what members with a similar age, genotype and bloodwork tried.

Example profileFemale55APOE4/4HbA1c 5.7%Fasting insulin 14 µIU/mL

12 members with a similar profile · 9 lowered fasting insulin

Berberine9 of 12
Zone-2 cardio · 3×/week7 of 12
Time-restricted eating6 of 12

2Your own results prove it

See what’s working. Adjust what isn’t.

Bring your bloodwork, wearable data and daily check-ins together. See what changed, then decide what to keep, adjust or measure for longer.

Cholesterol LDL-C mg/dL

168before

116now · −31%

Your next decision

Keep It’s working.
Adjust
Measure for longer

Works with what you already use

We partner with these companies to bring your data into one place, with an APOE4 lens

Apple Health iPhone
Google Health Connect Android

(soon)
Samsung Health
(soon)
Sleep Cycle
Xiaomi

And 52 more apps that sync through Apple Health and Google Health Connect

Stand on the shoulders of other APOE4 carriers.

Member experiments

Phoenix learns from every member’s experiments, then looks closest at the members most like you.

750+ APOE4 carriers

Every experiment and result, pooled

Members like you

Matched on your full health profile, for example

Genetic profile: APOE 4/4Caucasian
Bloodwork: High LDL-CPrediabetic
About you: FemaleAge 55–65Postmenopausal
Lifestyle: Poor sleepLow activity

What they tried, what worked and what did not

Mediterranean dietLDL-CImproved
Psyllium huskLDL-CImproved
KetoLDL-CWorse
Zone-2 cardioApoBImproved
Curcuminhs-CRPNo change
BerberineFasting insulinImproved
Omega-3 (DHA)Omega-3 indexImproved
Saunahs-CRPNo change
Strength trainingFasting insulinImproved
Coconut oilLDL-CWorse
Zetia (ezetimibe)LDL-CImproved
MagnesiumDeep sleepNo change

Phoenix AI

Phoenix AI learns from members’ results and from yours, and suggests the best protocol for you.

See how it works

1Your next step

Psyllium huskWorked for members with a similar profile

2Your results

LDL-C~~168~~ → 116−31%

Your experience adds to what we learn together.

You don’t have to make APOE4 your full-time job.

Your personal protocol, built around you.

Inspired by what worked for APOE4 carriers with a similar health profile. Validate what works for you through guided experiments.

Choose your next stepA personal protocol based on your genes and bloodwork.
You follow your protocol
See what’s working for youTrack your bloodwork and how you feel.
Your results refine your protocol

Explore your personal protocol

Your personal APOE4 protocol

Phoenix AI recommends your next step, learning from research and other APOE4 carriers.

Psyllium huskActive during improvement

Mediterranean dietActive during improvement

Zetia (ezetimibe)Ongoing experiment

ApoB

~~131 to~~ 69 ~~mg/dL~~

−47%

LDL-C

~~168 to~~ 68 ~~mg/dL~~

−60%

Optimize your bloodwork for APOE4.

Your lab can call a result fine before it reaches your APOE4 target. Upload your results and Phoenix checks every biomarker against its APOE4 target range, then tracks each retest.

See how you track progress

Now for members in the US: order blood tests in the app at Phoenix specially negotiated pricing, with each test, the blood-draw fee and the total shown before you pay. You can also upload results from any other lab to Core.

See how member testing works

Stay informed without spending hours researching.

We watch the new APOE4 research for you and tell you what matters, in plain language. No more digging through Facebook groups and Google. Bring your questions to expert Q&As.

Explore Phoenix research

Find clinical trials that fit your profile.

See relevant studies, recruitment updates and eligibility details in one place, with the contacts for your next step.

Explore clinical trials

Find doctors who understand APOE4.

Explore APOE4-aware providers and prepare for appointments with the right questions.

Find an APOE4-aware doctor

Keep going with people who get it.

Join a pod of APOE4 carriers with similar goals. Stay motivated and keep your momentum, with encouragement, support and accountability from people walking the same path.

Meet your community

A clear next step today. Support as your needs change.

Apply to join Phoenix

89% see improvement in key APOE4 biomarkers within 3 months

Self-reported

Turn the effort you’re already making into progress you can measure.

32% of members are healthcare professionals

Trusted by people who work in healthcare. Explore the science-based approach behind Phoenix.

92% monthly active users

Members keep using Phoenix because they see real value in it.

750+ APOE4 carriers

4 new members join us every day!

Hear what members value.

Joining the Phoenix group was huge for me

Dr. John YoderRetired physician

It is worth every penny

Melinda B.Registered nurse

It gives me hope

Donna D.Phoenix member

It’s a risk factor, not a sentence

Dr. Gertrude BehanRetired physician

The best activity that has helped the most

Patricia F.Phoenix member

That’s the best decision I have made

Julie C.Retired

Doing nothing is not really a good option

Jules WaltersLongevity coach

We spent three hours talking

Robin P. ShwetzerHealth coach

Explore all member stories

Phoenix only earns revenue from your membership, nothing else. This is how we stay 100% independent and unbiased.

We partner with carefully vetted providers for all your needs: neurologist, devices, bloodwork, supplements. But we never earn a single cent on what you buy. Any commission fee we could take goes to you instead, as a higher discount. That’s how members get blood tests up to 70% below retail and supplements up to 35% off. This guarantees you get the absolute best price possible for all your APOE4 needs.

This helps us remain completely independent, and allows us to truly personalize our protocol to each one of you, while never pushing you to test more or take more supplements.

As a patient and APOE4/4 carrier myself, I was sick (pun intended) of not being able to trust recommendations when I knew there was some financial incentive to promote something (hello AG1).

Phoenix is a carrier-first community. I don’t know if this model is sustainable, but I believe this is the right thing to do. And this matters to me when Phoenix is literally my own survival mission AND when I put my personal reputation on the line.

Dr. Kevin Tran, founder, APOE4/4

I carry two copies of APOE4.

I built Phoenix because I wanted to give myself the best chance of beating the odds. Now I’m building it for you too.

Dr. Kevin Tran · Doctor of Pharmacy · Founder

Read my story

Choose your next step with Phoenix.