A4LI: the longevity policy nonprofit,for APOE4 carriers
In its own words, the Alliance for Longevity Initiatives (A4LI) is “a 501(c)(4) nonprofit organization dedicated to advancing legislation and policies aimed at increasing healthy human lifespan, with a focus on accelerating equitable access to next-generation therapies.” Dylan V. Livingston founded it in 2022.
In episode 26 (November 19, 2025), Brenda Eap, PhD, talks with Kevin Tran, the founder of Phoenix: a Doctor of Pharmacy who carries two copies of APOE4.
They cover what learning his APOE4 result changed, why finding the right participants holds back Alzheimer’s trials, and what carriers can work on now: exercise, sleep, stress and diet.
A4LI works on legislation and policy for aging research. Here is its work as A4LI describes it, with a link to each part.
Three stated priorities
More federal funding for research on aging, clear FDA standards for medicines that target aging biology, and a national healthy life expectancy goal. A4LI states that less than 1% of the NIH budget goes to aging biology research.
A yearly summit in Washington, D.C. The third ran from June 29 to July 1, 2026, at Georgetown University’s Capitol Campus, with a congressional briefing on the last day.
A4LI names Alzheimer’s among the leading causes of death tied to aging. Policy shapes how research on aging gets funded and how new medicines get approved.
Phoenix works on what carriers can do today. Phoenix is the #1 APOE4 community optimizing their brain health: 750+ APOE4 carriers. Members keep their bloodwork, read against APOE4-specific targets, next to every supplement, medication and habit they change, so each retest shows what moved. You can find every APOE4-relevant clinical trial in the Clinical Trial Engine, read Phoenix research, see APOE4 Alzheimer’s risk by age, and read why Kevin built Phoenix.
Works with what you already use
We partner with these companies to bring your data into one place, with an APOE4 lens
Phoenix brings in your data from Apple Health, Google Health Connect and 60+ apps and devices, and reads it through an APOE4 lens.
Apple HealthiPhone
Google Health ConnectAndroid
(soon)
Samsung Health
(soon)
Sleep Cycle
Xiaomi
And 52 more apps that sync through Apple Health and Google Health Connect
Where Phoenix stands
Phoenix takes no position on any bill, candidate or party.
We link to A4LI because its podcast featured our founder and because its site explains its proposals in full. Read them there and make up your own mind.
Phoenix earns only from memberships and never takes a fee on what members buy.
Follow A4LI’s work
A4LI’s Get Involved page lists how to volunteer and take part. Its podcasts and policy papers are free.
What is the Alliance for Longevity Initiatives (A4LI)?
A4LI describes itself as a 501(c)(4) nonprofit whose mission is to advance legislation and policies that aim to increase healthy human lifespan, with a focus on accelerating equitable access to next-generation therapies. Dylan V. Livingston founded it in 2022.
What does A4LI do?
According to its website, A4LI publishes policy papers, works with the Longevity Science Caucus in the U.S. House, runs the yearly H-SPAN Summit in Washington, D.C., and hosts two podcasts: H-SPAN on longevity policy and Scientist Spotlight on aging researchers.
Why would an APOE4 community link to a longevity policy group?
A4LI says aging is the greatest risk factor for chronic disease, names Alzheimer’s among the leading causes of death tied to aging, and states that less than 1% of the NIH budget goes to aging biology research. Its site is a clear place to read the policy side of aging research, in its own words.
Does Phoenix endorse A4LI’s legislative positions?
No. Phoenix takes no position on any bill, candidate or party. We link to A4LI because its podcast featured our founder and because its site explains its proposals in full. Read them there and make up your own mind.
Where can I hear Kevin Tran on A4LI’s podcast?
On Scientist Spotlight episode 26 (November 19, 2025), hosted by Brenda Eap, PhD. Kevin, a Doctor of Pharmacy who carries two copies of APOE4, talks about learning his result, why trial recruitment matters for Alzheimer’s research, and building Phoenix, now the #1 APOE4 community optimizing their brain health with 750+ APOE4 carriers.
How can I follow A4LI’s work?
A4LI’s Get Involved page lists how to volunteer and take part, and its podcasts and policy papers are free to read and listen to. It is also on LinkedIn, X and YouTube.
Apple Health iPhone
Google Health Connect Android
(soon)
Samsung Health
(soon)
Sleep Cycle
Xiaomi