Beat the odds.
You have APOE4.
Now you have Phoenix.

Everything you need to outsmart Alzheimer’s, in one place.

60-day money-back guarantee

Your personal APOE4 protocol

Phoenix AI recommends your next step, learning from research and other APOE4 carriers.

  • Psyllium huskActive during improvement
  • Mediterranean dietActive during improvement
  • Zetia (ezetimibe)Ongoing experiment
ApoB 131→69mg/dL −47%
ApoB went from 131 to 69 mg/dL, inside the Phoenix APOE4 target range. Your lab’s “normal” range is wide; the Phoenix APOE4 target range is the lower part of it.
LDL-C 168→68mg/dL −60%

Learn from 708+ APOE4 carriers. See what helped, what didn’t, and what to try next. Your results add to what we learn together.

As seen in

  • SCMP (South China Morning Post)
  • Longevity.Technology
  • The Peak
  • The Alliance for Longevity Initiatives
  • Yahoo Finance
  • MarketWatch
  • Business Insider
  • Morningstar
  • GlobeNewswire

APOE4 carriers are too often forgotten by mainstream healthcare and research.

You want to act now. Too often, these are the answers you get.

  • “Come back when you have Alzheimer’s symptoms.”

    Neurologist

    So you wait for the thing you are trying to prevent.

  • “There’s nothing we can do.”

    Geneticist

    You leave with a result and no plan.

  • “What is APOE4?”

    Primary care

    You end up explaining your own gene to your doctor.

  • “Buy this magic pill!”

    Supplement industry

    Everyone has an answer. How do you pick what actually works for you?

You can’t afford to guess.

So you do your own research, and you’re left deciding what applies to you.

All of it sounds right.

None of it personalized to you. None of it validated to work on you.

You have APOE4. Now you have Phoenix.

Your personal protocol, the research that matters, and people who understand. Together in one place, so you can focus on your next step.

See what worked for carriers like you.
Then validate that it works for you.

What works for carriers like you is more likely to work for you.
Your own results then show whether it does.

1Carriers like you went first

A better starting point for your next step.

Compare what members with a similar age, genotype and bloodwork tried.

Example profileFemale55APOE4/4HbA1c 5.7%Fasting insulin 14 µIU/mL

12 members with a similar profile · 9 lowered fasting insulin

  • Berberine9 of 12
  • Zone-2 cardio · 3×/week7 of 12
  • Time-restricted eating6 of 12

2Your own results prove it

See what’s working. Adjust what isn’t.

Bring your bloodwork, wearable data and daily check-ins together. See what changed, then decide what to keep, adjust or measure for longer.

Cholesterol LDL-C mg/dL

168before

116now · −31%

Your next decision

  • Keep It’s working.

Stand on the shoulders of other APOE4 carriers.

Member experiments

Phoenix learns from every member’s experiments, then looks closest at the members most like you.

708+ APOE4 carriers

Every experiment and result, pooled

Members like you

Matched on your full health profile, for example

Genetic profile
APOE 4/4Caucasian
Bloodwork
High LDL-CPrediabetic
About you
FemaleAge 55–65Postmenopausal
Lifestyle
Poor sleepLow activity

What they tried, what worked and what did not

  • Mediterranean dietLDL-CImproved
  • Psyllium huskLDL-CImproved
  • KetoLDL-CWorse
  • Zone-2 cardioApoBImproved
  • Curcuminhs-CRPNo change
  • BerberineFasting insulinImproved
  • Omega-3 (DHA)Omega-3 indexImproved
  • Saunahs-CRPNo change
  • Strength trainingFasting insulinImproved
  • Coconut oilLDL-CWorse
  • Zetia (ezetimibe)LDL-CImproved
  • MagnesiumDeep sleepNo change

Phoenix AI

Phoenix AI learns from members’ results and from yours, and suggests the best protocol for you.

See how it works

1Your next step

Psyllium huskWorked for members with a similar profile

2Your results

LDL-C168 → 116−31%

Your experience adds to what we learn together.

You don’t have to make APOE4 your full-time job.

Your personal protocol, built around you.

Inspired by what worked for APOE4 carriers with a similar health profile. Validate what works for you through guided experiments.

  1. Choose your next stepA personal protocol based on your genes and bloodwork.
  2. You follow your protocol
  3. See what’s working for youTrack your bloodwork and how you feel.
  4. Your results refine your protocol
Explore your personal protocol

Your personal APOE4 protocol

Phoenix AI recommends your next step, learning from research and other APOE4 carriers.

Psyllium huskActive during improvement

Mediterranean dietActive during improvement

Zetia (ezetimibe)Ongoing experiment

ApoB

131 to 69 mg/dL

−47%
LDL-C

168 to 68 mg/dL

−60%

Optimize your bloodwork for APOE4.

Your lab can call a result fine before it reaches your APOE4 target. Upload your results and Phoenix checks every biomarker against its APOE4 target range, then tracks each retest.

See how you track progress

Now for members in the US: order blood tests in the app at Phoenix specially negotiated pricing, with each test, the blood-draw fee and the total shown before you pay. You can also upload results from any other lab to Core.

See how member testing works

Stay informed without spending hours researching.

Get the APOE4 research that matters, explained in plain language. Bring your questions to expert Q&As.

Explore Phoenix research

Find clinical trials that fit your profile.

See relevant studies, recruitment updates and eligibility details in one place, with the contacts for your next step.

Explore clinical trials

Find doctors who understand APOE4.

Explore APOE4-aware providers and prepare for appointments with the right questions.

Find an APOE4-aware doctor

Keep going with people who get it.

Join a pod of APOE4 carriers with similar goals. Stay motivated and keep your momentum, with encouragement, support and accountability from people walking the same path.

Meet your community

A clear next step today. Support as your needs change.

Membership figures

89% see improvement in key APOE4 biomarkers within 3 months

Turn the effort you’re already making into progress you can measure.

32% of members are healthcare professionals

Trusted by people who work in healthcare. Explore the science-based approach behind Phoenix.

92% monthly active users

Members keep using Phoenix because they see real value in it.

708+ APOE4 carriers

4 new members join us every day!

Hear what members value.

Joining the Phoenix group was huge for me

Dr. John YoderRetired physician

It is worth every penny

Melinda B.Registered nurse

It gives me hope

Donna D.Phoenix member

It’s a risk factor, not a sentence

Dr. Gertrude BehanRetired physician

The best activity that has helped the most

Patricia F.Phoenix member

That’s the best decision I have made

Julie C.Retired

Doing nothing is not really a good option

Jules WaltersLongevity coach

We spent three hours talking

Robin P. ShwetzerHealth coach

Explore all member stories

Phoenix APOE4 research.

Mainstream research too often forgets APOE4 carriers.
So we take matters into our own hands.

Phoenix studies what carriers try and how their results change,
to build our own data set of what works.

  • 476members
  • 30,737biomarker readings
  • 176intervention signals

See what we are learning together.

Report cover. APOE4: The Beat the Odds Study. The first results from the largest carrier-run APOE4 study in the world. Release 001, September 2026: 476 members, 30,737 biomarker readings, 176 intervention signals.

In my own words

I don’t want to leave my fate to someone else.

Dr. Kevin TranFounder · APOE4/4 carrier

Watch the full interview

Let’s build your APOE4 protocol together.

I carry two copies of APOE4. I built Phoenix because I wanted to give myself the best chance of beating the odds. Now I’m building it for you too.

Dr. Kevin Tran · Founder · Doctor of Pharmacy

Every membership includes blood-test ordering at Phoenix specially negotiated pricing (US) and the Phoenix private supplement store (up to 35% off in the US, 25% in Canada). Phoenix never earns a dollar on our recommendations, so we always stay fully unbiased.